Valuation : ISIS Pharmaceuticals, Inc.

Market Cap 9.95B 8.58B 8.09B 7.37B 13.77B 940B 13.88B 95.74B 37.16B 481B 37.37B 36.55B 1,579B P/E 2026 *
-16.4x
P/E 2027 * -31.7x
Enterprise Value 9.85B 8.5B 8B 7.29B 13.63B 930B 13.73B 94.75B 36.77B 476B 36.98B 36.17B 1,562B EV / Sales 2026 *
10.8x
EV / Sales 2027 * 7.14x
Free-Float
99.05%
Yield 2026 *
-
Yield 2027 * -
Manager TitleAgeSince
Investor Relations Contact 60 30/06/2012
Chief Executive Officer 64 31/12/2019
Director of Finance/CFO 64 30/04/2000
Director TitleAgeSince
Director/Board Member 64 12/12/2005
Director/Board Member 73 30/04/2002
Director/Board Member 64 24/03/2019
Change 5-day change 1-year change 3-year change Capi.($)
+1.33%+2.73% - - 9.95B
+0.97%-0.75%+3.51%+17.79% 49.74B
+0.18%-2.46%+431.57%+523.72% 44.98B
+2.45%+1.17%+43.99%+19.77% 42.52B
+1.06%-3.69%+9.01%+76.70% 40.78B
-0.90%-1.74%+15.20%+48.44% 32.89B
+2.54%+6.43% - - 17.09B
+1.52%-4.55%+24.83%+122.89% 16.28B
+1.70%-0.05%+18.53%+28.09% 14.4B
+2.95%-1.58%+80.12%+42.17% 13.48B
Average +1.40%-2.42%+78.35%+109.95% 30.24B
Weighted average by Cap. +1.16%-2.25%+94.39%+129.29%

Financials

2026 *2027 *
Net sales 913M 788M 742M 676M 1.26B 86.28B 1.27B 8.79B 3.41B 44.11B 3.43B 3.35B 145B 1.4B 1.21B 1.14B 1.04B 1.94B 132B 1.95B 13.49B 5.23B 67.71B 5.26B 5.15B 222B
Net income -602M -520M -490M -446M -834M -56.91B -840M -5.8B -2.25B -29.1B -2.26B -2.21B -95.58B -326M -281M -265M -241M -451M -30.78B -454M -3.14B -1.22B -15.74B -1.22B -1.2B -51.7B
Net Debt -103M -88.83M -83.68M -76.24M -143M -9.73B -144M -991M -384M -4.97B -387M -378M -16.34B 57.45M 49.57M 46.69M 42.54M 79.52M 5.43B 80.11M 553M 215M 2.77B 216M 211M 9.12B
Logo ISIS Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
Employees
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Trader
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Global
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Quality
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ESG MSCI
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