Valuation: Ionis Pharmaceuticals, Inc.

Capitalization 5.95B 5.16B 4.86B 4.42B 8.18B 516B 9.21B 57.61B 22.05B 236B 22.34B 21.87B 868B P/E ratio 2025 *
-12.1x
P/E ratio 2026 * -11.9x
Enterprise value 5.22B 4.53B 4.26B 3.88B 7.17B 452B 8.08B 50.5B 19.33B 207B 19.59B 19.17B 761B EV / Sales 2025 *
6.98x
EV / Sales 2026 * 6.33x
Free-Float
99.23%
Yield 2025 *
-
Yield 2026 * -
More valuation ratios * Estimated data
Dynamic Chart
1 day+1.08%
1 week+5.11%
Current month+11.64%
1 month+8.53%
3 months+14.30%
6 months+5.00%
Current year+7.01%
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1 week 34.78
Extreme 34.775
37.54
1 month 32
Extreme 32
37.6
Current year 23.95
Extreme 23.95
37.6
1 year 23.95
Extreme 23.95
52.34
3 years 23.95
Extreme 23.95
54.44
5 years 23.95
Extreme 23.95
64.37
10 years 19.59
Extreme 19.5927
86.58
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Manager TitleAgeSince
Chief Executive Officer 63 31/12/2019
Investor Relations Contact 59 30/06/2012
Director of Finance/CFO 63 30/04/2000
Director TitleAgeSince
Director/Board Member 70 31/08/2000
Director/Board Member 80 31/12/1993
Director/Board Member 63 12/12/2005
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Change 5d. change 1-year change 3-years change Capi.($)
+1.08%+5.11%-8.33%+6.10% 5.95B
+0.39%-1.51%+16.56%+14.23% 48.43B
-40.00%+142.71%+35,996.87%+3,297.09% 18.8B
-2.25%-8.36%+58.85%+86.98% 29.32B
+0.08%-1.38%-27.76%-21.44% 26.77B
+1.25%+0.87%-1.65%+20.79% 26.16B
+0.10%-1.36%+11.76%-17.45% 12.32B
-1.14%-4.17%+150.59% - 11.83B
+2.02%+0.56%-53.65%-27.08% 11.64B
+3.63%+3.57%+45.45%+110.80% 10.68B
Average -0.18%+13.54%+3,618.87%+385.56% 20.19B
Weighted average by Cap. -0.47%+11.60%+3,368.49%+346.57%
See all sector performances

Financials

2025 *2026 *
Net sales 748M 649M 611M 555M 1.03B 64.76B 1.16B 7.23B 2.77B 29.67B 2.81B 2.75B 109B 867M 752M 708M 643M 1.19B 75.07B 1.34B 8.39B 3.21B 34.39B 3.25B 3.18B 126B
Net income -481M -418M -393M -357M -661M -41.7B -745M -4.66B -1.78B -19.1B -1.81B -1.77B -70.22B -501M -434M -409M -372M -688M -43.37B -775M -4.85B -1.85B -19.87B -1.88B -1.84B -73.04B
Net Debt -734M -637M -600M -545M -1.01B -63.61B -1.14B -7.11B -2.72B -29.14B -2.76B -2.7B -107B -466M -404M -380M -346M -639M -40.32B -720M -4.5B -1.72B -18.47B -1.75B -1.71B -67.91B
More financial data * Estimated data
Logo Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. is engaged in ribonucleic acid (RNA)-targeted therapeutics. The Company has five marketed medicines and a pipeline in neurology, cardiology, and other areas of high patient need. It has nine medicines in Phase III development and multiple additional medicines in early and mid-stage development. The Company’s products include SPINRAZA, QALSODY, WAINUA, TEGSEDI and WAYLIVRA. SPINRAZA is used for the treatment of patients with spinal muscular atrophy (SMA), a progressive, debilitating and often fatal genetic disease. QALSODY is an antisense medicine that is used for the treatment of adult patients with superoxide dismutase 1 amyotrophic lateral sclerosis (SOD1-ALS), a rare, neurodegenerative disorder that causes progressive loss of motor neurons leading to death. WAINUA is a self-administered subcutaneous LIgand-Conjugated Antisense (LICA) medicine used for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (ATTRv-PN).
Employees
1,069
More about the company
Date Price Change Volume
20/06/25 37.41 $ +1.08% 2,290,642
18/06/25 37.01 $ +2.38% 1,964,511
17/06/25 36.15 $ +2.58% 1,621,640
16/06/25 35.24 $ -0.98% 1,716,622
13/06/25 35.59 $ -0.08% 1,483,999

Delayed Quote Nasdaq, June 20, 2025 at 09:00 pm

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Sell
Consensus
Buy
Mean consensus
OUTPERFORM
Number of Analysts
26
Last Close Price
37.41USD
Average target price
57.66USD
Spread / Average Target
+54.12%
Consensus

Quarterly revenue - Rate of surprise