Valuation: Valerio Therapeutics

Market Cap 280M 319M 264M 241M 451M 30.55B 454M 3.16B 1.22B 15.61B 1.2B 1.17B 50.16B P/E 2024
-0.47x
P/E 2025 -6.9x
Enterprise Value 287M 327M 271M 247M 462M 31.34B 466M 3.24B 1.26B 16.01B 1.23B 1.2B 51.46B EV / Sales 2024
15x
EV / Sales 2025 29x
Free-Float
78.43%
Yield 2024 *
-
Yield 2025 -
1 day+1.07%
1 week-2.75%
Current month-23.72%
1 month-26.78%
3 months+166.35%
6 months+400.88%
Current year+310.14%
1 week 0.54
Extreme 0.536
0.59
1 month 0.54
Extreme 0.536
0.78
Current year 0.1
Extreme 0.1025
0.98
1 year 0.06
Extreme 0.057
0.98
3 years 0.04
Extreme 0.0401
0.98
5 years 0.04
Extreme 0.0401
0.98
10 years 0.04
Extreme 0.0401
5.46
Manager TitleAgeSince
Chief Executive Officer - 30/06/2026
Chief Executive Officer 52 05/04/2022
Director of Finance/CFO - 28/02/2022
Director TitleAgeSince
Director/Board Member 63 28/06/2011
Chairman 43 12/11/2024
Chairman 66 -
Date Insider Type Main position Quantity % Market Cap. Importance
26/08/26 Buy 11,864,406 2.0900%
22/04/21 Buy 4,225,352 4.6244%
04/11/20 Buy 333 0.0004%
Change 5-day change 1-year change 3-year change Capi.($)
+1.07%-2.75%+875.86%+126.40% 319M
+0.13%+2.65%+63.34%+115.27% 1,055B
+0.20%+0.46%+50.92%+72.63% 654B
-0.29%+0.14%+19.82%+72.62% 467B
-2.29%-3.62%+37.29%+40.81% 348B
+0.96%+4.18%+22.16%+29.12% 275B
-0.42%-0.53%+12.68%+13.52% 258B
+2.11%+7.51%+51.88%+54.14% 224B
+0.83%+0.55%+34.64%+99.77% 187B
-0.23%-2.90%-28.18%-61.25% 171B
Average +0.17%+0.25%+114.04%+56.30% 363.87B
Weighted average by Cap. +0.10%+1.32%+39.93%+68.46%

Financials

2024 2025
Net sales 1.79M 2.04M 1.69M 1.54M 2.89M 196M 2.91M 20.26M 7.85M 100M 7.67M 7.51M 322M 2.57M 2.93M 2.43M 2.21M 4.15M 281M 4.18M 29.08M 11.26M 144M 11.01M 10.77M 461M
Net income -23.93M -27.27M -22.6M -20.6M -38.56M -2.61B -38.83M -270M -105M -1.34B -102M -100M -4.29B -4.9M -5.58M -4.63M -4.22M -7.89M -535M -7.95M -55.36M -21.44M -273M -20.96M -20.5M -878M
Net Debt 15.38M 17.53M 14.53M 13.24M 24.79M 1.68B 24.96M 174M 67.34M 858M 65.82M 64.4M 2.76B 7.26M 8.27M 6.86M 6.25M 11.7M 793M 11.78M 82.05M 31.78M 405M 31.06M 30.39M 1.3B
Logo Valerio Therapeutics
Valerio Therapeutics is a clinical-stage biotechnology company developing novel cancer drugs by targeting tumor DNA functions through unparalleled mechanisms of action in the highly sought-after field of DNA damage response (DDR). The company focuses on the development of innovative first-in-class or disruptive compounds (in-house, acquired or licensed) from translational research to human clinical proof of concept. Valerio Therapeutics has platON®, its proprietary decoy oligonucleotide chemistry platform, and V-Body, the platform for generating single-domain therapeutic antibodies. These two proprietary platforms are dedicated to the generation of innovative new compounds to enrich the company's product portfolio. AsiDNA® is the first compound derived from platON®, a first-in-class inhibitor developed by the company, and V-Body, the platform for generating single-domain therapeutic antibodies. These two proprietary platforms are dedicated. Based on a novel decoy and agonist mechanism acting upstream of multiple DDR pathways, it is highly differentiated from the tumor DNA damage response. Valerio Therapeutics is also developing VIO-01 (previously OX425), a novel platON®-generated drug candidate optimized to be a next-generation PARP inhibitor, acting on both the DNA damage response and the activation of the immune response, without inducing resistance. The clinical development of VIO-01 was stopped in early 2025 in order to redirect research and development efforts towards next-generation drug candidates based on the PlatON and VBody platforms.
Employees
25
Date Price Change Volume
28/09/26 €0.5660 +1.07% 155,243
25/09/26 €0.5600 +0.36% 368,996
24/09/26 €0.5580 -2.11% 371,277
23/09/26 €0.5700 -1.55% 254,760
22/09/26 €0.5790 -0.52% 335,304
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