On March 29, 2024, Alexander Asam, Ph.D. informed the Board of Directors of Mineralys Therapeutics, Inc. of his decision not to stand for re-election to the Board when his current term expires at the Company?s 2024 annual meeting of stockholders. Dr. Asam advised the Company that his decision was not the result of any disagreement with the Company or its management on any matter relating to the Company?s operations, policies or practices.