Gb Sciences has reported positive results from a study of its potential treatment for cytokine release syndrome (CRS), one of the most dangerous complications of COVID-19. With reports of the arrival of the Omicron variant of the coronavirus in multiple countries, the Gb Sciences team plans to move quickly through the development stages for this novel CRS therapy. Using its AI-driven drug discovery platform, Gb Sciences developed cannabinoid-containing complex mixtures (CCCM) designed to reduce the levels of specific cytokines and pro-inflammatory processes triggered by the COVID-19 virus, while preserving the immune functions and cytokines necessary to fight the disease. The study, completed by researchers at Michigan State University in August 2021, found that specific formulations of the CCCMs reduced cytokine release syndrome biomarkers. Mixtures of multiple synthetic molecules from cannabinoid plants performed better than single molecules alone, and the ratios of those molecules also influenced results, the company reported. The preclinical data indicates that the CCCMs may be effective anti-inflammatory therapies for CRS and other conditions such as macrophage activation syndrome (MAS) and acute respiratory distress syndrome (ARDS)-- all leading causes of death in COVID-19 patients.