Valuation : Denali Therapeutics Inc.

Market Cap 3.53B 3.04B 2.86B 2.61B 4.88B 336B 4.89B 33.89B 13.1B 171B 13.25B 12.97B 542B P/E 2026 *
-9.54x
P/E 2027 * -9.58x
Enterprise Value 2.82B 2.43B 2.29B 2.08B 3.9B 268B 3.91B 27.09B 10.47B 137B 10.59B 10.36B 433B EV / Sales 2026 *
56.1x
EV / Sales 2027 * 21.9x
Free-Float
90.04%
Yield 2026 *
-
Yield 2027 * -
1 day-1.99%
1 week-4.70%
Current month-8.35%
1 month-12.90%
3 months+4.74%
6 months+2.18%
Current year+31.89%
1 week 21.34
Extreme 21.34
23.02
1 month 21.34
Extreme 21.34
25.7
Current year 15.34
Extreme 15.34
27.3
1 year 12.58
Extreme 12.58
27.3
3 years 10.57
Extreme 10.57
33.33
5 years 10.57
Extreme 10.57
56.08
10 years 10.57
Extreme 10.57
93.94
Manager TitleAgeSince
Director of Finance/CFO 52 30/04/2022
Chief Executive Officer 50 31/07/2015
Chief Tech/Sci/R&D Officer 58 05/11/2025
Director TitleAgeSince
Director/Board Member 50 28/02/2015
Director/Board Member 73 31/03/2015
Director/Board Member 68 31/03/2015
Date Insider Type Main position Quantity % Market Cap. Importance
02/09/26 Sell

Director

-11,439 0.0072%
01/09/26 Sell

Founder

-2,768 0.0017%
12/08/26 Don

Founder

-32,220 0.0203%
Change 5-day change 1-year change 3-year change Capi.($)
-1.99%-4.70%+41.76%-9.01% 3.53B
-0.94%+0.31%+40.04%+103.25% 69.19B
-0.07%-3.93%+32.54%+75.96% 62.97B
+3.39%+2.16%-12.12%+388.15% 27.27B
-0.47%-5.53%-3.94%-16.85% 24.78B
-0.93%-1.29%+25.30%+16.70% 25.8B
-1.43%-1.89%+21.32%-17.67% 20.11B
-4.27%+2.67%+219.02%+362.48% 18.47B
-1.43%-1.80%-8.64%+537.09% 14.88B
+1.08%-1.00%+51.38%+163.52% 14.29B
Average -0.74%-0.78%+40.66%+160.36% 28.13B
Weighted average by Cap. -0.50%-0.82%+36.51%+139.22%

Financials

2026 *2027 *
Net sales 50.26M 43.24M 40.72M 37.1M 69.42M 4.78B 69.69M 483M 187M 2.44B 189M 185M 7.72B 127M 109M 103M 93.67M 175M 12.07B 176M 1.22B 471M 6.15B 476M 466M 19.49B
Net income -454M -391M -368M -336M -628M -43.24B -630M -4.36B -1.69B -22.03B -1.71B -1.67B -69.8B -453M -389M -367M -334M -625M -43.06B -628M -4.35B -1.68B -21.94B -1.7B -1.66B -69.5B
Net Debt -708M -610M -574M -523M -979M -67.41B -982M -6.8B -2.63B -34.34B -2.66B -2.6B -109B -749M -644M -607M -553M -1.03B -71.24B -1.04B -7.19B -2.78B -36.29B -2.81B -2.75B -115B
Logo Denali Therapeutics Inc.
Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology.
Employees
503
Date Price Change Volume
09/09/26 US$21.78 -1.36% 1,381,973
08/09/26 US$22.08 -0.90% 1,653,769
04/09/26 US$22.28 -2.28% 799,633
03/09/26 US$22.80 -0.22% 1,727,981
02/09/26 US$22.85 -1.78% 1,768,603
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
20
Last Close Price
22.08USD
Average target price
36.06USD
Spread / Average Target
+63.33%

Quarterly revenue - Rate of surprise

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