Agilent Technologies Inc. announced it is investing approximately $725 million to double manufacturing capacity of therapeutic nucleic acids in response to rapid growth of the $1 billion market and strong demand for the company's high-quality active pharmaceutical ingredients (API). Therapeutic nucleic acids, also called therapeutic oligonucleotides or oligos, are short DNA and RNA molecules that serve as the API for drugs targeting a growing number of diseases, including cancer, cardiovascular disease, and rare and infectious diseases. The new Train C and D manufacturing lines will be based in Agilent's Frederick, Colorado facility, where a Train B manufacturing line, announced in 2020, will go live later this year.

Agilent's therapeutic oligo facilities follow current good manufacturing practices (cGMP), and the expanded facility will employ advanced automation and engineering enhancements, including water reduction and solvent capturing and recycling. Read more about Agilent's oligo API development and manufacturing services and background on oligos for therapeutics in Agilent's media room.