Total Brain Limited entered a perpetual, non-exclusive license with Alto Neuroscience Inc. for its iSpot-D (International Study to Predict Optimized Treatment for Depression) research data, effective immediately. Total Brain will receive a one-off license fee of USD 500K payable USD 100k by 15 January 2022 and USD 400k within 15 days of the data transfer date which is estimated to occur before March 31, 2022. The transaction is subject to conventional commercial termination provisions.