Through an agreement with National Health Service (
Efmoroctocog alfa is licensed by the
"Today's announcement is exciting news for the haemophilia A community in the
Previously many people living with haemophilia A in the
Treatment guidelines recently published by the
"Our Liberate Life vision means putting people living with haemophilia and how they want to lead their lives at the front of clinical decision making. People with haemophilia should feel able to live more active lives, through an approach tailored to their specific needs, activity levels and aspirations," continued Wood.
The new framework agreement will commence on
About haemophilia A
Haemophilia is a rare, genetic disorder in which the ability of a person's blood to clot is impaired. Haemophilia A occurs in about one in 5,000 male births annually, and more rarely in females.
Prophylactic injections of factor VIII and factor IX can temporarily replace the clotting factors that are needed to control bleeding and prevent new bleeding episodes.
About Elocta®
Elocta® (efmoroctocog alfa) is a recombinant clotting factor therapy developed for haemophilia A using Fc fusion technology to prolong circulation in the body. It is engineered by fusing factor VIII to the Fc portion of immunoglobulin G subclass 1, or IgG1 (a protein commonly found in the body), enabling Elocta to use a naturally occurring pathway to extend the time the therapy remains in the body (half-life). Elocta is manufactured using a human cell line in an environment free of animal and human additives.
Elocta is approved and marketed by Sobi for the treatment of haemophilia A in the EU,
As with any factor replacement therapy, allergic-type hypersensitivity reactions and development of inhibitors may occur in the treatment of haemophilia A. Inhibitor development has been observed with Elocta, including in previously untreated patients. Note that the indication for previously untreated patients is not included in the EU Product Information for Elocta.
About Sobi
Sobi is a specialised international biopharmaceutical company transforming the lives of people with rare diseases. Sobi is providing sustainable access to innovative therapies in the areas of haematology, immunology and specialty indications. Today, Sobi employs approximately 1,400 people across
For more information please contact
Paula Treutiger, Head of Communication & Investor Relations
+ 46 733 666 599
paula.treutiger@sobi.com
+ 46 708 734 095
linda.holmstrom@sobi.com
(1) ELOCTA[® ]Summary of Product Characteristics. Available at https://www.medicines.org.uk/emc/product/5100/smpc. Last accessed
(2) Rayment et al. Guidelines on the use of prophylactic factor replacement for children and adults with Haemophilia A and B. 2020: 6, 7. https://b-s-h.org.uk/guidelines/guidelines/the-use-of-prophylactic-factor-replacement-for-children-and-adults-with-haemophilia-a-and-b/
(3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130100/
Postal address SE-112 76
Phone: 46 8 697 20 00 www.sobi.com
https://news.cision.com/swedish-orphan-biovitrum-ab/r/successful-elocta-bid-means-increased-access-for-people-with-haemophilia-a-in-the-uk,c3142005
https://mb.cision.com/Main/14266/3142005/1269837.pdf
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