Soliton, Inc. announced that the company initiated a second pre-clinical study in animals for potential treatment of liver fibrosis intending to validate the first animal study that demonstrated positive results for the potential treatment of liver fibrosis. This additional pre-clinical study will seek to confirm the positive findings of Soliton's initial pre-clinical study in animals. The methods and conditions of the first study will remain the same in this second study. In the initial study, validated laboratory and histological assessments in a mouse model demonstrated that Rapid Acoustic Pulse (RAP) therapy reduced the effects of induced liver fibrosis 7-days following completion of carbon tetrachloride (CCL4) induction by 42%. Post treatment histology slides stained with picrosirius red (PSR) showed a lower percentage of fibrosis from a single 2-minute RAP treatment than the Control group. The RAP device is currently cleared by the FDA for short-term improvement in the appearance of cellulite. The RAP device is also indicated for use as an accessory to the 1064 nm Q-Switched laser for black ink tattoo removal in Fitzpatrick Skin Type I-III patients. The device is not yet cleared for the treatment of liver fibrosis.