The board of directors of Sirnaomics Ltd. announces that the Board has received a letter of resignation from Mr. Da Liu ("Mr. Liu") to resign as a non-executive Director with effect from September 30, 2022, as Mr. Liu wishes to devote more time to his other commitments. Mr. Liu has confirmed that he had no disagreement with the Board and there were no other matters relating to his resignation that need to be brought to the attention of the shareholders of the Company or The Stock Exchange of Hong Kong Limited.