Regarding the research and development of the nasal vaccine as adopted, we are going to pursue research including the optimization of vaccine composition and elucidation of immune mechanisms in cooperation with
A nasal vaccine has the merits of being noninvasive, of being able to effectively induce antibody production in the respiratory mucosa, the site of initial infection, which are difficult to induce with conventional intramuscularly injected vaccines. Therefore, nasal vaccination is expected not only to prevent the onset and decrease the severity of infectious disease symptoms, but also to prevent the initial viral infection itself.
About SCARDA
SCARDA is an organization established within the
About HanaVax's cationic nanogel delivery system (cCHP)
Mucosal immunity is of great importance for the prevention of respiratory system infections because the respiratory mucosa is the first line of defense against pathogens. HanaVax's proprietary cationic nanogel delivery formulation provides a protective carrier for antigens consisting of a polysaccharide pullulan molecule modified with cholesterol and cationic amines. The nanogel increases the retention time of antigens on the mucosal surface and increases gradual uptake by immune cells. This effectively initiates the induction of both mucosal and systemic immunity.
Forward-Looking Statements
This announcement contains forward-looking statements. These statements are based on expectations in light of the information currently available, assumptions that are subject to risks and uncertainties which could cause actual results to differ materially from these statements. Risks and uncertainties include general domestic and international economic conditions such as general industry and market conditions, and changes of interest rate and currency exchange rate. These risks and uncertainties particularly apply with respect to product-related forward-looking statements. Product risks and uncertainties include, but are not limited to, completion and discontinuation of clinical trials; obtaining regulatory approvals; claims and concerns about product safety and efficacy; technological advances; adverse outcome of important litigation; domestic and foreign healthcare reforms and changes of laws and regulations. Also for existing products, there are manufacturing and marketing risks, which include, but are not limited to, inability to build production capacity to meet demand, lack of availability of raw materials and entry of competitive products. The company disclaims any intention or obligation to update or revise any forward-looking statements whether as a result of new information, future events or otherwise.
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