Protagonist Therapeutics Appoints Scott Plevy, M.D., Executive Vice President and Therapeutic Head, Gastroenterology
September 07, 2021 at 12:00 pm
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Protagonist Therapeutics, Inc. announced the appointment of Scott Plevy, M.D., to the role of Executive Vice President and Therapeutic Head, Gastroenterology. Dr. Plevy will oversee clinical operations and development of Protagonist's ongoing and future programs in gastrointestinal (GI) diseases, including PN-943, an investigational drug candidate currently in a Phase 2 study in ulcerative colitis. Dr. Plevy is a gastroenterologist and molecular immunologist who most recently served as Chief Scientific Officer at Senda Biosciences. He previously held the role of Chief Scientific Officer at Synlogic Therapeutics, and also served as Vice President, Immunology Research and Development at Janssen Pharmaceuticals, where he contributed to the discovery, development, launch and label expansion of several important drugs, including Stelara. Since the start of his career, Dr. Plevy has published over 110 peer-reviewed scientific papers in areas including novel immunologic interventions in inflammatory bowel disease and other immunologic disorders.
Protagonist Therapeutics, Inc. is a biopharmaceutical company. The Company uses its peptide-based chemical entities rusfertide and JNJ-2113 in different stages of development, all derived from its proprietary discovery technology platform. The Companyâs clinical programs fall into two categories of diseases: hematology and blood disorders, and inflammatory and immunomodulatory diseases. Its lead clinical asset, rusfertide (PTG-300), is an injectable hepcidin mimetic in development for the potential treatment of polycythemia vera (PV) and other blood disorders. The Companyâs Interleukin-23 receptor (IL-23R) antagonist compound JNJ-2113 is an orally delivered investigational drug that is designed to block biological pathways targeted by marketed injectable antibody drugs. Its PN-943 is a wholly owned investigational orally delivered gut-restricted alpha 4 beta 7 (α4β7) specific integrin antagonist for inflammatory bowel disease (IBD).