Valuation : Protagonist Therapeutics, Inc.

Market Cap 9.59B 8.26B 7.82B 7.09B 13.3B 916B 13.37B 92.91B 35.73B 466B 36.01B 35.22B 1,473B P/E 2026 *
31.9x
P/E 2027 * -312x
Enterprise Value 9.05B 7.8B 7.38B 6.69B 12.56B 865B 12.62B 87.69B 33.72B 440B 33.99B 33.24B 1,390B EV / Sales 2026 *
16.7x
EV / Sales 2027 * 44.6x
Free-Float
97.68%
Yield 2026 *
-
Yield 2027 * -
1 day+2.08%
1 week+1.69%
Current month+0.29%
1 month-0.07%
3 months+34.97%
6 months+53.59%
Current year+69.66%
1 week 142
Extreme 142
151.18
1 month 141.95
Extreme 141.9479
160.81
Current year 77
Extreme 77
160.81
1 year 57.9
Extreme 57.9
160.81
3 years 13.72
Extreme 13.72
160.81
5 years 6.91
Extreme 6.91
160.81
10 years 4.47
Extreme 4.47
160.81
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 69 30/06/2016
Date Insider Type Main position Quantity % Market Cap. Importance
10/09/26 Exercice

Chief Executive Officer

21,834 0.0337%
03/09/26 Don

Chief Executive Officer

-510 0.0008%
11/08/26 Exercice

Chief Executive Officer

102,717 0.1597%
Change 5-day change 1-year change 3-year change Capi.($)
+2.08%+1.69%+148.29%+685.68% 9.59B
-0.71%-6.35%-4.87%+9.03% 45.48B
+0.21%-2.98%+340.68%+519.93% 43.69B
+1.74%-2.24%+37.28%+21.57% 43.09B
+1.38%-3.28%+3.23%+65.60% 39.4B
-1.44%-5.26%+8.78%+36.85% 31.91B
+0.87%-2.60% - - 17.31B
+0.75%-0.64%+18.07%+110.32% 16.4B
-0.31%-2.78%+10.47%+30.49% 14.24B
+1.93%-3.55%+74.20%+39.37% 13.28B
Average +0.65%-3.05%+70.68%+168.76% 27.44B
Weighted average by Cap. +0.47%-3.48%+75.96%+144.53%

Financials

2026 *2027 *
Net sales 542M 467M 442M 401M 752M 51.81B 756M 5.25B 2.02B 26.36B 2.04B 1.99B 83.28B 203M 175M 166M 150M 282M 19.43B 284M 1.97B 758M 9.89B 764M 747M 31.24B
Net income 324M 279M 264M 239M 449M 30.93B 451M 3.14B 1.21B 15.74B 1.22B 1.19B 49.72B -32.12M -27.68M -26.21M -23.75M -44.56M -3.07B -44.79M -311M -120M -1.56B -121M -118M -4.93B
Net Debt -538M -464M -439M -398M -747M -51.42B -750M -5.22B -2.01B -26.16B -2.02B -1.98B -82.67B -511M -440M -417M -378M -709M -48.83B -713M -4.95B -1.9B -24.84B -1.92B -1.88B -78.49B
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
141
Date Price Change Volume
11/09/26 US$148.18 +2.08% 478,038
10/09/26 US$145.16 +0.05% 543,129
09/09/26 US$145.09 -0.58% 530,534
08/09/26 US$145.94 +0.15% 700,126
04/09/26 US$145.72 -2.07% 501,305
Trader
Investor
Global
Quality
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
13
Last Close Price
148.18USD
Average target price
174.69USD
Spread / Average Target
+17.89%

Quarterly revenue - Rate of surprise

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