Valuation: Protagonist Therapeutics, Inc.

Market Cap 8.45B 7.39B 6.82B 6.3B 11.95B 806B 12.15B 81.47B 32B 397B 31.73B 31.04B 1,365B P/E 2026 *
33.6x
P/E 2027 * -115x
Enterprise Value 7.88B 6.89B 6.36B 5.87B 11.14B 751B 11.33B 75.94B 29.82B 370B 29.58B 28.94B 1,272B EV / Sales 2026 *
15.4x
EV / Sales 2027 * 48.5x
Free-Float
97.28%
Yield 2026 *
-
Yield 2027 * -
1 day-4.52%
1 week-0.15%
Current month+7.21%
1 month+24.25%
3 months+32.99%
6 months+63.82%
Current year+50.47%
1 week 128.15
Extreme 128.15
141.1
1 month 108.53
Extreme 108.53
141.1
Current year 77
Extreme 77
141.1
1 year 50.48
Extreme 50.485
141.1
3 years 13.72
Extreme 13.72
141.1
5 years 6.91
Extreme 6.91
141.1
10 years 4.47
Extreme 4.47
141.1
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 69 30/06/2016
Date Insider Type Main position Quantity % Market Cap.
06-22Fiscal year

Director

27,000 0.0420%
06-09Fiscal year

Director

27,000 0.0420%
05-28Fiscal year

Director

27,000 0.0420%
Change 5-day change 1-year change 3-year change Capi.($)
-4.52%-0.15%+148.78%+459.71% 8.45B
+0.58%+2.06%+2.92%+10.86% 50.73B
-2.22%-1.25%+385.40%+586.81% 39.73B
-0.54%+0.39%+25.57%-5.28% 34.69B
-1.36%+0.35%+17.88%+55.14% 33.21B
+1.21%-4.58%+3.00%+35.46% 26.76B
-1.81%-1.48% - - 16.8B
+0.51%-3.47%+63.97%+122.60% 15.37B
+0.23%-0.58%+13.76%+21.11% 13.78B
-0.62%-3.09%+10.29%-31.35% 12.85B
Average -0.85%-0.76%+74.62%+139.45% 25.24B
Weighted average by Cap. -0.62%-0.23%+83.14%+136.35%

Financials

2026 *2027 *
Net sales 510M 446M 412M 380M 721M 48.65B 733M 4.92B 1.93B 23.97B 1.92B 1.87B 82.4B 163M 142M 131M 121M 230M 15.52B 234M 1.57B 616M 7.64B 611M 598M 26.28B
Net income 259M 227M 209M 193M 367M 24.74B 373M 2.5B 982M 12.19B 974M 953M 41.9B -82.92M -72.53M -66.9M -61.79M -117M -7.91B -119M -799M -314M -3.9B -311M -305M -13.39B
Net Debt -574M -502M -463M -428M -811M -54.74B -825M -5.53B -2.17B -26.97B -2.15B -2.11B -92.7B -565M -494M -456M -421M -798M -53.86B -812M -5.44B -2.14B -26.53B -2.12B -2.07B -91.22B
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
131
Date Price Change Volume
10/07/26 US$131.42 -4.52% 1,060,849
09/07/26 US$137.64 -1.73% 1,613,332
08/07/26 US$140.07 -0.55% 931,358
07/07/26 US$140.85 +7.11% 1,374,383
06/07/26 US$131.50 -0.09% 640,087
Trader
Investor
Global
Quality
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
13
Last Close Price
131.42USD
Average target price
120.54USD
Spread / Average Target
-8.28%

Quarterly revenue - Rate of surprise

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