Valuation: Protagonist Therapeutics, Inc.

Market Cap 8.77B 7.93B 7.32B 6.63B 12.51B 825B 12.88B 87.88B 34.92B 441B 32.92B 32.22B 1,403B P/E 2026 *
26.6x
P/E 2027 * 665x
Enterprise Value 8.19B 7.41B 6.84B 6.19B 11.68B 770B 12.03B 82.1B 32.63B 412B 30.76B 30.1B 1,311B EV / Sales 2026 *
14.5x
EV / Sales 2027 * 34.1x
Free-Float
97.64%
Yield 2026 *
-
Yield 2027 * -
1 day-0.36%
1 week-0.65%
Current month-7.23%
1 month-7.25%
3 months-11.60%
6 months+34.45%
Current year+53.86%
1 week 131.26
Extreme 131.265
138.82
1 month 126.39
Extreme 126.39
146.44
Current year 77
Extreme 77
160.81
1 year 77
Extreme 77
160.81
3 years 15.58
Extreme 15.58
160.81
5 years 6.91
Extreme 6.91
160.81
10 years 4.47
Extreme 4.47
160.81
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 68 30/06/2016
Date Insider Type Main position Quantity % Market Cap. Importance
30/09/26 Exercice

Chief Financial Officer

175,887 0.2718%
10/09/26 Exercice

Chief Executive Officer

21,834 0.0337%
03/09/26 Don

Chief Executive Officer

-510 0.0008%
Change 5-day change 1-year change 3-year change Capi.($)
-0.36%-0.65%+58.37%+767.53% 8.77B
+1.10%-2.67%+62.79%+70.47% 68.45B
+1.28%+8.71%+13.96%+95.16% 61.31B
+0.36%-0.95%+20.09%+99.04% 55.73B
-0.96%+7.41%+10.20%+108.91% 47.51B
-1.25%+2.35%+22.74%+38.34% 44.68B
-2.41%-0.73%+167.89%+794.72% 38.14B
+1.21%-2.56%+20.27%+52.81% 35.85B
-0.87%-2.89%+79.60%+63.96% 33.05B
-2.22%+8.56%-39.26%+397.14% 25.9B
Average -0.41%+2.34%+41.66%+248.81% 42B
Weighted average by Cap. -0.16%+2.77%+40.61%+177.41%

Financials

2026 *2027 *
Net sales 566M 512M 473M 428M 807M 53.23B 832M 5.67B 2.25B 28.46B 2.13B 2.08B 90.58B 240M 217M 201M 182M 343M 22.59B 353M 2.41B 957M 12.07B 902M 882M 38.43B
Net income 353M 319M 295M 267M 503M 33.17B 518M 3.54B 1.4B 17.73B 1.32B 1.3B 56.44B 32.9M 29.75M 27.46M 24.86M 46.91M 3.09B 48.32M 330M 131M 1.65B 123M 121M 5.26B
Net Debt -576M -521M -481M -435M -822M -54.17B -846M -5.77B -2.29B -28.96B -2.16B -2.12B -92.18B -567M -513M -473M -429M -809M -53.32B -833M -5.68B -2.26B -28.5B -2.13B -2.08B -90.73B
Projected Income Statement - Annual - Protagonist Therapeutics, Inc.
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
149
Date Price Change Volume
12/11/26 US$134.38 -0.36% 542,899
11/11/26 US$134.86 -1.03% 332,592
10/11/26 US$136.26 +0.26% 528,491
09/11/26 US$135.90 +2.92% 607,111
06/11/26 US$132.04 -2.38% 972,945
Trader
Investor
Global
Quality
ESG MSCI
BB
MarketScreener Ratings - Protagonist Therapeutics, Inc.
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
14
Last Close Price
134.38USD
Average target price
182.36USD
Spread / Average Target
+35.70%
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