Valuation: Protagonist Therapeutics, Inc.

Market Cap 9.38B 8.11B 7.58B 6.95B 13.08B 893B 13.28B 88.91B 34.9B 448B 35.23B 34.46B 1,479B P/E 2026 *
31.2x
P/E 2027 * -208x
Enterprise Value 8.81B 7.62B 7.11B 6.53B 12.28B 838B 12.47B 83.47B 32.76B 420B 33.07B 32.35B 1,389B EV / Sales 2026 *
16.3x
EV / Sales 2027 * 46.3x
Free-Float
97.3%
Yield 2026 *
-
Yield 2027 * -
1 day-0.21%
1 week+6.75%
Current month+6.75%
1 month+3.56%
3 months+47.57%
6 months+72.65%
Current year+67.01%
1 week 131.68
Extreme 131.68
148
1 month 125.32
Extreme 125.3225
148
Current year 77
Extreme 77
148
1 year 50.58
Extreme 50.58
148
3 years 13.72
Extreme 13.72
148
5 years 6.91
Extreme 6.91
148
10 years 4.47
Extreme 4.47
148
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 69 30/06/2016
Date Insider Type Main position Quantity % Market Cap.
10/06/26 Fiscal year

Director

27,000 0.0420%
17/02/26 Fiscal year

Director

54,000 0.0864%
06/02/26 Fiscal year

Director

60,000 0.0960%
Change 5-day change 1-year change 3-year change Capi.($)
-0.21%+6.75%+186.24%+670.58% 9.38B
+0.99%+1.78%+4.07%+16.73% 49.47B
+3.71%+9.40%+486.98%+592.14% 43.61B
+5.60%+10.21%+16.76%+85.72% 39.6B
+2.70%+1.57%+33.39%+8.85% 39.29B
+2.21%+6.75%+21.31%+53.37% 32.43B
+2.23%+4.71% - - 16.84B
+0.97%+2.35%+37.75%+126.84% 16.49B
-0.11%+2.41%+6.24%+18.87% 14.01B
+0.75%+15.04%+78.59%+30.30% 12.77B
Average +1.88%+6.36%+96.82%+178.16% 27.39B
Weighted average by Cap. +2.45%+6.12%+107.25%+160.12%

Financials

2026 *2027 *
Net sales 542M 469M 438M 401M 755M 51.56B 767M 5.13B 2.02B 25.84B 2.03B 1.99B 85.44B 191M 165M 154M 141M 266M 18.14B 270M 1.81B 709M 9.09B 716M 700M 30.05B
Net income 322M 278M 260M 238M 449M 30.63B 456M 3.05B 1.2B 15.35B 1.21B 1.18B 50.75B -50.04M -43.28M -40.42M -37.08M -69.74M -4.76B -70.85M -474M -186M -2.39B -188M -184M -7.89B
Net Debt -574M -496M -464M -425M -800M -54.62B -813M -5.44B -2.13B -27.38B -2.16B -2.11B -90.51B -565M -488M -456M -418M -787M -53.75B -800M -5.35B -2.1B -26.94B -2.12B -2.07B -89.06B
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
131
Date Price Change Volume
07/08/26 US$145.87 -0.21% 321,084
06/08/26 US$146.18 +6.45% 837,630
05/08/26 US$137.32 +1.11% 430,528
04/08/26 US$135.81 +2.67% 634,672
03/08/26 US$132.28 -3.19% 451,166
Trader
Investor
Global
Quality
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
13
Last Close Price
145.87USD
Average target price
150.54USD
Spread / Average Target
+3.20%

Quarterly revenue - Rate of surprise

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