Valuation: Protagonist Therapeutics, Inc.

Market Cap 8.8B 7.93B 7.33B 6.63B 12.54B 826B 12.85B 87.84B 35.01B 442B 33.04B 32.33B 1,407B P/E 2026 *
26.7x
P/E 2027 * 667x
Enterprise Value 8.23B 7.41B 6.85B 6.19B 11.72B 772B 12B 82.09B 32.72B 413B 30.87B 30.22B 1,315B EV / Sales 2026 *
14.5x
EV / Sales 2027 * 34.3x
Free-Float
96.86%
Yield 2026 *
-
Yield 2027 * -
1 day-1.03%
1 week-5.94%
Current month-6.90%
1 month-6.17%
3 months-9.06%
6 months+30.30%
Current year+54.41%
1 week 128
Extreme 128
138.4
1 month 126.39
Extreme 126.39
146.44
Current year 77
Extreme 77
160.81
1 year 77
Extreme 77
160.81
3 years 15.05
Extreme 15.05
160.81
5 years 6.91
Extreme 6.91
160.81
10 years 4.47
Extreme 4.47
160.81
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 68 30/06/2016
Date Insider Type Main position Quantity % Market Cap. Importance
30/09/26 Exercice

Chief Financial Officer

175,887 0.2718%
10/09/26 Exercice

Chief Executive Officer

21,834 0.0337%
03/09/26 Don

Chief Executive Officer

-510 0.0008%
Change 5-day change 1-year change 3-year change Capi.($)
-1.03%-5.94%+57.62%+770.63% 8.89B
-1.06%-0.07%+60.76%+68.61% 68.32B
+1.30%+7.41%+14.79%+92.69% 60.26B
+0.39%+0.30%+20.04%+98.33% 55.86B
-0.95%+11.17%+22.21%+110.93% 48.43B
-0.23%+4.07%+25.63%+40.08% 45.34B
-6.40%-9.51%+181.99%+816.79% 41.76B
+1.97%+3.50%+25.78%+50.98% 34.5B
-0.56%-0.48%+85.57%+65.40% 33.8B
+0.08%+0.74%+47.00%+0.49% 25.96B
Average -0.62%+1.26%+54.14%+211.49% 42B
Weighted average by Cap. -0.59%+1.62%+50.84%+160.47%

Financials

2026 *2027 *
Net sales 566M 510M 472M 426M 806M 53.11B 826M 5.65B 2.25B 28.44B 2.13B 2.08B 90.52B 240M 217M 200M 181M 342M 22.53B 351M 2.4B 956M 12.07B 902M 882M 38.4B
Net income 353M 318M 294M 266M 502M 33.09B 515M 3.52B 1.4B 17.72B 1.32B 1.3B 56.4B 32.9M 29.65M 27.4M 24.77M 46.86M 3.09B 48.01M 328M 131M 1.65B 123M 121M 5.26B
Net Debt -576M -519M -480M -434M -821M -54.05B -841M -5.75B -2.29B -28.95B -2.16B -2.12B -92.11B -567M -511M -472M -427M -808M -53.19B -828M -5.66B -2.26B -28.49B -2.13B -2.08B -90.66B
Projected Income Statement - Annual - Protagonist Therapeutics, Inc.
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
149
Date Price Change Volume
11/11/26 US$134.86 -1.03% 332,589
10/11/26 US$136.26 +0.26% 528,491
09/11/26 US$135.90 +2.92% 607,111
06/11/26 US$132.04 -2.38% 972,945
05/11/26 US$135.26 -5.66% 584,678
Trader
Investor
Global
Quality
ESG MSCI
BB
MarketScreener Ratings - Protagonist Therapeutics, Inc.
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
14
Last Close Price
134.86USD
Average target price
182.36USD
Spread / Average Target
+35.22%
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