Valuation: Protagonist Therapeutics, Inc.

Market Cap 9.4B 8.16B 7.64B 6.99B 13.19B 896B 13.36B 89.37B 35.07B 447B 35.3B 34.53B 1,489B P/E 2026 *
30.9x
P/E 2027 * -259x
Enterprise Value 8.83B 7.66B 7.17B 6.56B 12.39B 841B 12.55B 83.91B 32.93B 420B 33.14B 32.42B 1,398B EV / Sales 2026 *
16.3x
EV / Sales 2027 * 44.2x
Free-Float
97.28%
Yield 2026 *
-
Yield 2027 * -
1 day+6.45%
1 week+5.44%
Current month+6.98%
1 month+11.16%
3 months+40.60%
6 months+73.01%
Current year+67.37%
1 week 131.68
Extreme 131.68
148
1 month 125.32
Extreme 125.3225
148
Current year 77
Extreme 77
148
1 year 50.48
Extreme 50.485
148
3 years 13.72
Extreme 13.72
148
5 years 6.91
Extreme 6.91
148
10 years 4.47
Extreme 4.47
148
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 69 30/06/2016
Date Insider Type Main position Quantity % Market Cap.
10/06/26 Fiscal year

Director

27,000 0.0420%
17/02/26 Fiscal year

Director

54,000 0.0864%
06/02/26 Fiscal year

Director

60,000 0.0960%
Change 5-day change 1-year change 3-year change Capi.($)
+6.45%+5.44%+171.38%+662.15% 9.4B
+0.93%-0.63%+3.89%+14.93% 48.7B
+0.26%+2.93%+439.43%+533.80% 42.05B
-1.53%-2.25%+30.95%+7.15% 38.26B
+0.69%+2.40%+10.48%+63.05% 37.5B
+2.47%+2.63%+14.71%+48.37% 31.44B
-0.47%+1.16%+35.93%+126.09% 16.33B
+2.31%-0.49% - - 16.47B
+0.29%+1.87%+8.17%+18.60% 13.98B
-1.43%-2.63%+3.70%-36.38% 12.43B
Average +1.00%+0.82%+79.85%+159.75% 26.66B
Weighted average by Cap. +0.67%+0.44%+92.23%+141.65%

Financials

2026 *2027 *
Net sales 542M 471M 441M 403M 761M 51.67B 771M 5.16B 2.02B 25.82B 2.04B 1.99B 85.93B 200M 174M 163M 149M 281M 19.06B 284M 1.9B 746M 9.52B 751M 735M 31.7B
Net income 319M 276M 259M 237M 447M 30.35B 453M 3.03B 1.19B 15.16B 1.2B 1.17B 50.47B -34.19M -29.67M -27.78M -25.41M -47.97M -3.26B -48.6M -325M -128M -1.63B -128M -126M -5.42B
Net Debt -574M -498M -466M -427M -805M -54.67B -816M -5.46B -2.14B -27.32B -2.15B -2.11B -90.92B -565M -490M -459M -420M -792M -53.8B -803M -5.37B -2.11B -26.88B -2.12B -2.07B -89.46B
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
131
Date Price Change Volume
06/08/26 US$146.18 +6.45% 837,613
05/08/26 US$137.32 +1.11% 430,528
04/08/26 US$135.81 +2.67% 634,672
03/08/26 US$132.28 -3.19% 451,166
31/07/26 US$136.64 -1.44% 548,764
Trader
Investor
Global
Quality
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
13
Last Close Price
146.18USD
Average target price
150.54USD
Spread / Average Target
+2.98%

Quarterly revenue - Rate of surprise

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