Valuation: Protagonist Therapeutics, Inc.

Market Cap 8.62B 7.73B 7.06B 6.45B 12.15B 810B 12.53B 85.15B 33.95B 432B 32.35B 31.65B 1,365B P/E 2026 *
27.1x
P/E 2027 * 1,320x
Enterprise Value 8.09B 7.26B 6.63B 6.05B 11.41B 761B 11.77B 79.94B 31.88B 406B 30.37B 29.72B 1,281B EV / Sales 2026 *
14.1x
EV / Sales 2027 * 35.4x
Free-Float
97.68%
Yield 2026 *
-
Yield 2027 * -
1 day-2.38%
1 week-8.84%
Current month-8.84%
1 month-6.30%
3 months-9.48%
6 months+33.58%
Current year+51.18%
1 week 128
Extreme 128
146
1 month 126.39
Extreme 126.39
152.18
Current year 77
Extreme 77
160.81
1 year 77
Extreme 77
160.81
3 years 14.78
Extreme 14.78
160.81
5 years 6.91
Extreme 6.91
160.81
10 years 4.47
Extreme 4.47
160.81
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 69 30/06/2016
Date Insider Type Main position Quantity % Market Cap. Importance
30/09/26 Exercice

Chief Financial Officer

175,887 0.2718%
10/09/26 Exercice

Chief Executive Officer

21,834 0.0337%
03/09/26 Don

Chief Executive Officer

-510 0.0008%
Change 5-day change 1-year change 3-year change Capi.($)
-2.38%-8.84%+66.00%+701.70% 8.62B
-4.83%+3.51%+55.00%+63.79% 66.7B
+0.02%+1.07%+11.72%+75.63% 56.88B
-1.34%+2.98%+25.08%+100.18% 56.53B
+5.09%+9.89%+27.19%+105.85% 46.49B
+2.62%+1.68%+29.16%+35.86% 44.8B
+8.24%+0.51%+215.16%+794.74% 41.59B
-1.86%+10.13%+28.14%+55.48% 35.35B
-2.97%-9.84%+90.91%+73.49% 33.29B
+5.19%+1.62%-39.69%+368.87% 25.1B
Average +0.78%+1.50%+50.87%+237.56% 41.53B
Weighted average by Cap. +0.59%+2.83%+50.24%+176.99%

Financials

2026 *2027 *
Net sales 572M 513M 469M 428M 806M 53.77B 832M 5.65B 2.25B 28.69B 2.15B 2.1B 90.57B 229M 206M 188M 172M 323M 21.56B 334M 2.27B 904M 11.51B 861M 843M 36.32B
Net income 346M 311M 284M 259M 488M 32.57B 504M 3.42B 1.37B 17.38B 1.3B 1.27B 54.86B 46.25M 41.48M 37.91M 34.61M 65.2M 4.35B 67.26M 457M 182M 2.32B 174M 170M 7.32B
Net Debt -527M -473M -432M -394M -743M -49.53B -766M -5.21B -2.08B -26.43B -1.98B -1.94B -83.43B -494M -443M -405M -370M -697M -46.46B -719M -4.88B -1.95B -24.79B -1.86B -1.82B -78.25B
Projected Income Statement - Annual - Protagonist Therapeutics, Inc.
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
132
Date Price Change Volume
06/11/26 US$132.04 -2.38% 972,945
05/11/26 US$135.26 -5.66% 584,678
04/11/26 US$143.37 +2.23% 777,232
03/11/26 US$140.24 +0.62% 674,722
02/11/26 US$139.37 -3.78% 486,660
Trader
Investor
Global
Quality
ESG MSCI
BB
MarketScreener Ratings - Protagonist Therapeutics, Inc.
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
14
Last Close Price
132.04USD
Average target price
182.21USD
Spread / Average Target
+38.00%

Quarterly revenue - Rate of surprise

Rate of surprise - Net sales - Quarterly - Protagonist Therapeutics, Inc.
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