Valuation : Protagonist Therapeutics, Inc.

Market Cap 9.8B 8.41B 7.9B 7.21B 13.61B 935B 13.68B 93.46B 36.22B 472B 36.81B 36.01B 1,562B P/E 2026 *
33x
P/E 2027 * -300x
Enterprise Value 9.27B 7.96B 7.47B 6.82B 12.88B 884B 12.94B 88.4B 34.26B 446B 34.81B 34.06B 1,478B EV / Sales 2026 *
17.2x
EV / Sales 2027 * 46x
Free-Float
97.68%
Yield 2026 *
-
Yield 2027 * -
1 day+0.60%
1 week-2.22%
Current month+10.88%
1 month+11.31%
3 months+51.53%
6 months+71.40%
Current year+73.46%
1 week 147.69
Extreme 147.69
158.08
1 month 130.63
Extreme 130.63
160.81
Current year 77
Extreme 77
160.81
1 year 54.5
Extreme 54.5
160.81
3 years 13.72
Extreme 13.72
160.81
5 years 6.91
Extreme 6.91
160.81
10 years 4.47
Extreme 4.47
160.81
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 69 30/06/2016
Date Insider Type Main position Quantity % Market Cap.
11/08/26 Fiscal year

Chief Executive Officer

102,717 0.1597%
10/06/26 Fiscal year

Director

27,000 0.0420%
17/02/26 Fiscal year

Director

54,000 0.0864%
Change 5-day change 1-year change 3-year change Capi.($)
+0.60%-2.22%+165.84%+660.54% 9.8B
-0.31%+0.17%+2.52%+23.41% 50.96B
+1.92%+0.36%+477.97%+550.09% 46.18B
-0.15%-0.28%+21.65%+89.41% 42.73B
+0.81%+4.91%+39.28%+19.41% 43.04B
-2.27%-3.02%+14.22%+51.50% 33.48B
+0.81%+1.77%+31.91%+138.26% 17.28B
-1.08%-3.61% - - 16.43B
-0.27%-0.27%+11.45%+28.21% 14.73B
-0.85%+1.76%+80.26%+47.26% 14.09B
Average +0.00%+0.98%+93.90%+178.68% 28.87B
Weighted average by Cap. +0.17%+1.04%+105.65%+157.63%

Financials

2026 *2027 *
Net sales 538M 462M 434M 396M 747M 51.33B 751M 5.13B 1.99B 25.9B 2.02B 1.98B 85.77B 202M 174M 163M 149M 281M 19.3B 282M 1.93B 748M 9.74B 760M 743M 32.25B
Net income 320M 275M 258M 235M 444M 30.52B 446M 3.05B 1.18B 15.4B 1.2B 1.18B 51B -34.44M -29.56M -27.74M -25.34M -47.82M -3.28B -48.05M -328M -127M -1.66B -129M -127M -5.49B
Net Debt -531M -456M -428M -391M -738M -50.68B -741M -5.07B -1.96B -25.57B -2B -1.95B -84.68B -503M -432M -405M -370M -699M -47.99B -702M -4.8B -1.86B -24.21B -1.89B -1.85B -80.19B
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
141
Date Price Change Volume
26/08/26 US$151.50 +0.60% 335,462
25/08/26 US$150.59 -2.67% 664,526
24/08/26 US$154.72 +0.26% 483,342
21/08/26 US$154.32 +2.41% 402,542
20/08/26 US$150.69 -2.74% 518,560
Trader
Investor
Global
Quality
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
13
Last Close Price
151.50USD
Average target price
170.38USD
Spread / Average Target
+12.47%

Quarterly revenue - Rate of surprise

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