OPKO Health, Inc. announced that it ahs entered into non-dilutive note purchase agreement with new investor Healthcare Royalty Management, LLC to issue a convertible note for the gross proceeds of $250,000,000 on July 17, 2024. The note issued under the Note Purchase Agreement bears interest at the 3-month Secured Overnight Financing Rate (SOFR) subject to a 4% per annum floor, plus 7.5% per annum. The note has a final maturity date of July 2044 with the first four years requiring interest only payments.