Ensysce Biosciences, Inc. announced the Site Initiation Visit (SIV) was completed for the PF614-201 study, 'A Randomized, Double-Blind, Placebo-Controlled Crossover Study of PF614 on Analgesic Response in the Cold Pressor Test in Healthy male Subjects' to evaluate time of onset for PF614. The study is being conducted by Dr. George Atiee at Dr. Vince Clinical Research (DVCR) in Overland, KS. Each study serves a critical purpose and this new study's importance is grounded in the ability to best determine optimal prescribing options for surgical patients, while also key in preparing for full Phase 3 evaluation of PF614.

PF614 is a chemically modified opioid product that requires initial metabolic transformation by trypsin in the small intestine for activation to be able to relieve severe pain in patients who require an opioid-level analgesic. The company believe PF614 will be a game changer for the treatment of severe pain and represents a new generation of pain products.