Business description: Arrowhead Pharmaceuticals, Inc.

Arrowhead Pharmaceuticals, Inc. develops medicines that treat intractable diseases by silencing the genes that cause them. The Company's therapies, using a broad portfolio of ribonucleic acid (RNA) chemistries and modes of delivery, trigger the RNA interference (RNAi) mechanism to induce rapid, deep and durable knockdown of target genes. The Company's Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. It is focused on various therapeutic areas, such as cardiometabolic, pulmonary, liver, muscle and central nervous system. It has around 14 clinical-stage investigational medicines (nine wholly owned and five partnered), which range in development stage from Phase I to Phase III. The Company's pipeline products include Plozasiran, Zodasiran, Olpasiran, ARO-RAGE, ARO-MUC5AC, ARO-MMP7, GSK-4532990, Fazirsiran, JNJ-3989, HZN-457, ARO-C3, ARO-PNPLA3, ARO-DUX4 and ARO-SOD1.

Number of employees: 711

Sales by Activity: Arrowhead Pharmaceuticals, Inc.

Fiscal Period: September20212022202320242025

Nanotechnology

138M 243M 241M - 829M
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Geographical breakdown of sales: Arrowhead Pharmaceuticals, Inc.

Fiscal Period: September20212022202320242025

United States

138M 243M 241M - 829M
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Executive Committee: Arrowhead Pharmaceuticals, Inc.

Manager TitleAgeSince
Chief Executive Officer 55 30/11/2007
Director of Finance/CFO - 12/05/2025
Chief Tech/Sci/R&D Officer - 31/07/2022
Compliance Officer 61 30/11/2014
Chief Tech/Sci/R&D Officer 47 31/01/2025
See ARROWHEAD PHARMACEUTICALS, INC. governance

Composition of the Board of Directors: Arrowhead Pharmaceuticals, Inc.

Director TitleAgeSince
Chairman 55 -
Director/Board Member 65 18/08/2010
Director/Board Member 65 18/12/2011
Director/Board Member 68 31/12/2017
Director/Board Member 80 31/08/2020
Director/Board Member 61 01/05/2022
Director/Board Member 54 31/03/2024
Director/Board Member 62 05/02/2025
Composition of the Board of Directors

Shareholders: Arrowhead Pharmaceuticals, Inc.

NameEquities%Valuation
BlackRock Advisors LLC
13.94 %
19,271,815 13.94 % 817 M $
Vanguard Fiduciary Trust Co.
11.6 %
16,035,870 11.6 % 680 M $
Avoro Capital Advisor LLC
7.884 %
10,900,000 7.884 % 462 M $
4.627 %
6,397,364 4.627 % 271 M $
Fidelity Management & Research Co. LLC
4.166 %
5,759,830 4.166 % 244 M $
List of ARROWHEAD PHARMACEUTICALS, INC. shareholders

Company details: Arrowhead Pharmaceuticals, Inc.

Arrowhead Pharmaceuticals, Inc.

177 East Colorado Boulevard

91105, Pasadena

+626 304 3400

http://www.arrowheadpharma.com
address Arrowhead Pharmaceuticals, Inc.(ARWR)

Bio Therapeutic Drugs

Change 5d. change 1-year change 3-years change Capi.($)
-4.98%+16.58%+175.52%+93.09% 8.78B
-2.68%-1.46%+30.24%+105.16% 56.54B
-0.51%-1.81%+170.81%+925.64% 43.73B
+0.90%-0.87%+75.84%+15.31% 37.82B
+0.26%-6.69%-19.01%-42.27% 23.08B
-1.45%-0.34%+30.97%-37.78% 19.82B
-0.97%+4.69%+98.42%-40.74% 17.43B
+0.57%+0.98%+89.61%+302.27% 14.61B
-2.66%+2.35%+4.51%+2,232.48% 14.51B
+2.45%+0.79%+147.98% - 13.45B
Average -0.91%+1.02%+80.49%+394.80% 24.98B
Weighted average by Cap. -0.88%-0.57%+75.45%+347.77%
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