Adaptive Biotechnologies Corporation will be included in several oral and poster presentations investigating the clinical significance of minimal residual disease (MRD) assessment at the American Society of Clinical Oncology (ASCO) Annual Meeting taking place June 2-6 in Chicago, as well as the European Hematology Association (EHA) Hybrid Congress taking place June 8-11 in Frankfurt, Germany. Data will be presented from clinical trials and real-world evidence studies using Adaptive's next-generation sequencing (NGS)-based clonoSEQ® Assay for MRD assessment across a range of hematologic cancers. This assessment is performed as a series of tests in clinical trials and throughout a patient's cancer journey.

The clonoSEQ Assay is the first and only NGS-MRD test authorized by the U.S. Food and Drug Administration (FDA) for MRD assessment in certain hematologic malignancies. Presentations will also highlight the value of utilizing NGS-MRD testing in clinical trials to assess the effectiveness of investigational, novel therapeutics. Multiple Myeloma: Oral Abstract 8001: Maintenance therapy with carfilzomib, pomalidomide, and dexamethasone (KPd) in high-risk myeloma (pts): A phase 2 study with a safety run-in: 1:15-4:15 p.m. CDT: Measurable residual disease (MRD) and clonal diversity for multiple myeloma treatment monitoring.