X4 Pharmaceuticals, Inc. Announces the Appointment of Art Taveras as Chief Scientific Officer
November 02, 2020 at 03:42 pm
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X4 Pharmaceuticals, Inc. announced the appointment of Art Taveras, Ph.D., as Chief Scientific Officer. Dr. Taveras will lead all research and non-clinical development functions supporting the company's pipeline of investigational therapies. r. Taveras brings more than 30 years of experience leading small molecule research and development programs focused on the treatment of cancer, dysregulated immune disorders, neurodegeneration and metabolic diseases. His research and leadership have led to the development of multiple clinical candidates and dozens of clinical trials. He joins X4 from CoMET Therapeutics, where he served as Chief Scientific Officer. Previously, he was the Founder and Chief Scientific Officer at Transform Therapeutics, a company aiming to discover CXCR2 antagonists for the treatment of cancer, and served as President and Chief Scientific Officer at ShangPharma ChemPartner where he supported the discovery initiatives and clinical portfolios of hundreds of pharmaceutical and biotech companies worldwide. Prior to that, Dr. Taveras was Vice President of Small Molecule Drug Discovery and CMC Development at Biogen Idec, and Alantos Pharmaceuticals, which was acquired by Amgen in 2007. Dr. Taveras began his career with Schering-Plough Corporation and held multiple roles of increasing responsibility in the oncology and immunology drug discovery and research sector over a 14-year period including leading the discovery of Navarixin(R), a CXCR2 antagonist currently in clinical trials in combination with pembrolizumab for the treatment of cancer.
X4 Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on discovering and developing novel therapeutics for the treatment of rare diseases and those with limited treatment options, with a focus on conditions resulting from dysfunction of the immune system. Its lead clinical candidate is mavorixafor, a small-molecule selective antagonist of chemokine receptor CXCR4, that is being developed as an oral, once-daily therapy. It has developed a pipeline of small-molecule, oral antagonists of the chemokine receptor C-X-C receptor type 4 (CXCR4). It has two pre-clinical candidates: X4P-003, a second-generation CXCR4 antagonist designed to have enhanced properties relative to mavorixafor, potentially enabling opportunities in CXCR4-dependent disorders and primary immunodeficiencies, and X4P-002, a CXCR4 antagonist with a distribution profile and a demonstrated ability to cross the blood-brain barrier.