Item 5.02           Departure of Directors or Certain Officers; Election of Directors;
                    Appointment of Certain Officers; Compensatory Arrangements of Certain
                    Officers

On November 11, 2021, René Russo resigned from the Board of Directors (the "Board") of X4 Pharmaceuticals, Inc. (the "Company"), effective immediately. Ms. Russo's resignation from the Board was not due to any disagreement with the Company on any matter relating to the Company's operations, policies or practices.

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