Twist Bioscience Corporation announced an agreement with the Broad Institute to make available a whole exome target enrichment panel to enable next-generation sequencing (NGS) in canine genomics research. The panel, known as the Twist Alliance Canine Exome Panel, is available for order and will begin shipping in February 2022. The Twist Alliance Canine Exome is the most current commercial exome-scale assay available for canine NGS research, and is based on updated content from CanFam v3.1. The panel was collaboratively designed with the Vertebrate Genomics Group at the Broad Institute by leveraging Twist's rapid, iterative and flexible NGS platform to provide a rapid, off-the-shelf solution covering all coding exons of canine genes.

In addition to exon-centric content, the assay includes regions of known importance in human cancers. When used with Twist's robust end-to-end target enrichment workflows it enables cost-effective comparative studies between human and canine genomics to drive further insight into both human and canine health.