Trevi Therapeutics, Inc. announced the appointment of David Clark, MD, MRCP, as Chief Medical Officer (CMO). Dr. Clark will join Trevi's executive team and be responsible for the strategy and execution of Haduvio's clinical programs. Dr. Clark joins Trevi with over 25 years of global clinical development experience in big pharma and biotech. Most recently, Dr. Clark served as Chief Medical Officer at Allena Pharmaceuticals, leading the Company's clinical development, regulatory and medical affairs teams. Prior to that, he served as Chief Medical Officer for various companies, including Aldeyra Therapeutics, Wilson Therapeutics, and NormOxys.

As Chief Medical Officer, Dr. Clark has strategized and supported teams from clinical translation through Phase 3. He has also held senior leadership positions at TransTech Pharma, Pfizer, SmithKline Beecham, and GlaxoSmithKline. Dr. Clark holds a Bachelor of Medicine and Surgery (MD) from the University of Edinburgh Medical School, and a Membership of the Royal College of Physicians (MRCP). Dr. Clark also completed a research fellowship in respiratory medicine in the United Kingdom.

Dr. Thomas Sciascia, MD, the co-founder of Trevi Therapeutics, previously served as Trevi's Chief Medical Officer and will be transitioning to Chief Science Officer. His background as a board-certified neurologist and his experience with the development of Haduvio to date provides a deep understanding of Haduvio's mechanism. Dr. Sciascia's extensive knowledge of Haduvio will be applied to strengthen the continued exploration of Haduvio in serious chronic cough conditions.