Item 2.02. Results of Operations and Financial Condition.

On January 23, 2020, the Registrant issued a press release, a copy of which is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On January 21, 2020, Marty Casteel, 68, a director and senior executive vice president of Simmons First National Corporation ("Company"), as well as the chairman, president, and chief executive officer of the Company's wholly-owned subsidiary bank, Simmons Bank ("Bank"), informed the Company and Bank of his intent to retire from his employment with the Company and Bank, effective March 31, 2020. Mr. Casteel will continue to serve as a director of the Company and Bank and will be eligible to receive non-executive director compensation for such service following his retirement.

In addition, on January 21, 2020, Patrick Burrow, 66, executive vice president, general counsel, and secretary of the Company and Bank, also informed the Company and Bank of his intent to retire, effective March 31, 2020.

Item 9.01. Financial Statements and Exhibits.

Exhibit 99.1 . Press release dated January 23, 2020

Exhibit 104. Cover Page Interactive Date File (embedded within the Inline XBRL Document)

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