Satellos Bioscience Inc. announced that it has created, prioritized and advanced novel small molecule drug candidates into further preclinical studies. The Company's compounds have been designed to be potent and selective inhibitors of a particular kinase protein in the Notch pathway which the company is calling K9 for reasons of confidentiality. The Company's scientists have discovered that inhibiting this target enables the modulation of the muscle stem cell division and regeneration process in its lead disease indication, Duchenne muscular dystrophy ("Duchenne").

The Company's plan is to evaluate and prioritize these compounds for absorption, distribution, metabolism and excretion (ADME), pharmacokinetics (PK) and in vivo efficacy. The Company's goal is to finalize these studies and analysis by the end of 2022 in order to choose prospective lead and back-up drug candidates for IND-enabling drug development studies.