Satellos Bioscience Inc. announced that it has designated SAT-3153 for development towards an IND filing. SAT-3153 is a small molecule designed by Satellos to inhibit a particular kinase protein which the company believes controls Notch polarity within muscle stem cells. The Company's scientists have previously shown that muscle stem cell polarity is compromised in Duchenne, leading to a deficit in the body's innate ability to regenerate muscle.

Satellos believes this finding explains the progresive muscle destruction which characterizes Duchenne as the body cannot repair itself as intented. The Company's scientists have shown in preclinical studies that inhibiting this kinase protein target enables the modulation of polarity and muscle stem cell divisions, enhances muscle regeneration, and increases muscle mass and critically, muscle function.