On December 28, 2017, Intrexon Corporation (Intrexon) and Third Security, LLC (Third Security) executed an amendment (the Third Amendment) to the Services Agreement, dated as of November 1, 2015, and amended on October 31, 2016 and December 30, 2017 (as amended, the Services Agreement), by and between Intrexon and Third Security, in order to extend the term of the Services Agreement from January 1, 2018 to January 1, 2019. No other terms of the Services Agreement were modified by the Third Amendment, which became effective on January 1, 2018. The Third Amendment was unanimously approved by the independent members of Intrexon's Board of Directors and the Audit Committee of the Board in accordance with Intrexon's policy on related person transactions.