OptiNose, Inc. announced that it has entered into a $100 million debt financing agreement with funds managed by Athyrium Capital Management, LP. At closing of the agreement, $75 million in aggregate principal amount of the Senior Secured Notes were issued. An additional $25 million will be available to Optinose in 2019 subject to the achievement of a sales milestone and certain other conditions. The Senior Secured Notes mature in June 2023.