NorthIsle Copper and Gold : Intersects 84.8m grading 1.20g/t Au Eq including 25m grading 1.46g/t Au Eq in High Grade Gold-rich Porphyry Zone at Northwest Expo

January 24, 2022

TSX Venture Exchange Symbol: NCX

Northisle Intersects 84.8m grading 1.20g/t Au Eq including 25m grading 1.46g/t Au Eq

in High Grade Gold-rich Porphyry Zone at Northwest Expo

Highlights:

• Drilling confirms a trend of gold-rich copper porphyry mineralization covering 480 meters strike length by 360 meters dip length with an average width of 86 meters and open in multiple directions
• Grades in the gold-rich zone at Northwest Expo in the range of three to five times higher than those at Hushamu and Red Dog
• Assays for five drill holes at Northwest Expo remain pending that are targeting the eastern extent of interpreted large porphyry-related alteration system
• Northwest Expo is approximately 3km to the northwest of Red Dog and not part of current resources

Vancouver, B.C. - Northisle Copper and Gold Inc. (TSX-V: NCX) ("Northisle" or the "Company") is pleased to announce that it has received the first assay results from its 2021 drill program at Northwest Expo confirming a zone of high-grade,gold-rich porphyry mineralization approximately 3 kilometers northwest of its Red Dog Deposit. In addition, preliminary surface geophysical surveys at Macintosh have identified numerous chargeability and resistivity anomalies. Northisle commenced drill testing these anomalies on January 19, 2022 and anticipates completion during Q1 2022. In addition, Northisle recently completed 4 holes at Hushamu, and will continue in-fill and step-out drilling following completion of drilling at Macintosh.

Sam Lee, President & CEO of Northisle stated "We are pleased with the results at Northwest Expo to date which demonstrates the potential to add higher grade resources to the North Island Project. This gold-rich zone is not within the current resource at the North Island Project and is only 14 kilometers from the proposed plant site. Grades in the new zone are approximately three to five times higher than the grades at Hushamu and Red Dog which could have a positive impact on project economics and support our belief that we are just scratching the surface of the potential of our 50km camp scale porphyry belt."

Robin Tolbert, Vice President Exploration of Northisle added "With the receipt of assay results from NW21-03,we have now defined an area of approximately 480 meters by 360 meters of porphyry copper-goldmineralization, with an interpreted average width of 86 meters, and this volume is open in multiple directions. This is just the beginning of exploration on Northwest Expo. A ground-basedgeophysical program is scheduled to commence shortly and will allow targeting of an expanded drill program, to commence upon receipt of permits. The positive assay results have confirmed the regional interpretation of the importance of the chlorite-magnetitemineralization in this area, which will help to inform our approach to exploring the rest of our large and prospective land package." He added, "I am very excited to get back in the field during Q1 to test the drill targets identified by recent geophysical surveys at Macintosh and continue to see immense opportunities across our more than 33,000 hectares of exploration tenure."

Northisle Copper and Gold Inc. | 1200 - 1166 Alberni St. | Vancouver, BC | V6E 3Z3

www.northisle.ca|[e-mail]

Summary of High-Grade Gold Rich Porphyry Zone Results

Intercepts of the high-grade gold zone are summarized in Table 1.

Table 1: Zone 1 Significant Intercepts

Hole ID	From	To (m)	Interval	True	Au Grade	Cu Grade	Mo Grade	Re Grade	Au Eq.
	(m)		(m)	Width (m)	(g/t)	(%)	(%)	(g/t)	Grade (g/t)
NW21-03	280.25	365.05	84.8	84.0	0.92	0.19	0.005	0.17	1.20
Including	280.3	305.0	24.8	24.8	1.30	0.10	0.007	0.30	1.46
EC-218	323.8	438	114.2	114.0	0.53	0.11	0.004	*	0.70
EC-228	151.85	221.9	70.1	70.0	1.15	0.22	0.018	*	1.52
EC-233	329.2	423.7	94.5	94.0	0.86	0.13	0.002	*	1.04
EC-234	286.5	384.0	97.5	97.5	0.94	0.16	0.003	*	1.18
EC-245	148.0	264.9	116.9	110.0	1.18	0.15	0.001	*	1.80
Including	234.7	264.9	30.2	28.4	2.03	0.25	0.001	*	2.37
EC08-254	270.00	386.00	116.0	95.0	1.00	0.17	0.005	0.37	1.26
Including	322.0	352.0	30.0	24.6	1.50	0.21	0.008	0.24	1.82

• Not analyzed in historical drilling. Bolded holes are from 2021 drilling
  Copper and gold equivalent calculations based on the following metal prices which were used in the Company's 2021 PEA on the North Island Project: Cu = US$3.25/lb, Au = US$1,650/oz, Mo = US$10/lb, Re = $1,256/kg. Calculations assume 100% recovery; totals may not add due to rounding
  Note on equivalent calculation:
  Copper equivalent is determined by calculating total contained metal value/ tonne, dividing by the copper price, and then dividing the resultant number of pounds of copper by 2204.6. Gold equivalent is determined by calculating total contained metal value/tonne, dividing by the gold price, and then multiplying the resultant number of troy ounces of gold by 31.103

Figure 1 below shows the location of Company's exploration targets relative to the existing resources at Hushamu and Red Dog.

Figure 1: North Island Project Resource and Target Locations

Figure 1 can be found at full size at the following link: http://www.northisle.ca/wp-content/uploads/2022/01/Figure-1-Northisle-Project-Location-220113.pdf

Northisle Copper and Gold Inc. | 1200 - 1166 Alberni St. | Vancouver, BC | V6E 3Z3

www.northisle.ca|[e-mail]

Northwest Expo Details

Northwest Expo has been the subject of several drill programs dating back to at least 2005. Current exploration is focused on gaining a better understanding of three zones, labelled Zone 1, Zone 2, and Zone 3. Zone 1 contains significant intercepts of gold-rich copper porphyry mineralization and is a compelling target for near-term exploration. Zone 2 exhibits extensive faulting and may represent a down faulted block. Zone 3 contains historic drill intercepts of significant (>0.1 % Cu) copper-gold porphyry mineralization from 91 metres to 176 metres in length. Two holes were drilled in 2021 in this area with assays pending.

The objective of the 2021 program at Northwest Expo was to drill test anomalies indicated by limited induced polarization (IP) geophysical surveys completed in 2012. A review of historical drilling from 2005 and 2007, and updated with additional data from 2008, identified several intercepts of economically significant gold and copper which are detailed below. Figure 2: Northwest Expo Zones and shows the location of 2021 drilling at Northwest Expo in the context of historical drilling. The previous IP geophysics identified a 550 m wide chargeability anomaly (>15mV/V) extending south from a line running northeast from 5619500 North (north of DDH EC245) to 571400 East (northeast of DDH NW21-02). This anomaly is open to the northeast. The IP/Mag survey planned to commence in Q2 2022 will cover that un-surveyed area.

To date, assays for NW21-03 and NW21-04 have been received. NW21-03 is detailed, along with nearby historical drill holes in Zone 1, in Table 1. NW21-04 had no significant intercepts but provided a better understanding of Zone 2. NW21- 05 and NW21-08 (assays pending) are also assigned to Northwest Expo Zone 2, while NW21-01 and NW21-02 are targeting an un-drilled area of Zone 3.

The observed styles of alteration and mineralization in drill holes at Northwest Expo are consistent with the current hypothesis that this porphyry system is tilted to the southwest so that the core of the porphyry system lies to the northeast.

A plan view Northwest Expo, showing the above drill holes, can be found in Figure 2 below.

Figure 2: Northwest Expo Zones and Drill Holes

Northisle Copper and Gold Inc. | 1200 - 1166 Alberni St. | Vancouver, BC | V6E 3Z3

www.northisle.ca|[e-mail]

Figure 2 can be found at full size at the following link: http://www.northisle.ca/wp-content/uploads/2022/01/Figure-2-Zone-1-3-V8.pdf

Collar data for the relevant drill holes in Zones 1, 2 and 3 can be found on the Company's website here.

Figure 3: Extent of Northwest Expo silica-clay-pyrite (SCP) alteration and significant drill holes

Figure 3 can be found at full size at the following link: http://www.northisle.ca/wp-content/uploads/2022/01/Figure-3.jpg

Zone 1 - Gold-rich Porphyry Target

This zone is underlain by Jurassic Bonanza Formation andesitic volcaniclastics, flows and feldspar porphyry dykes and minor diorite with intense silica-clay-pyrite alteration imposed upon them, as well as hydrothermal breccias and silica immiscibility textured rocks emanating from an aerially extensive hydrothermal system. Mineralization occurs predominantly in characteristic chlorite-magnetite altered rocks (CMG) which is identical to the mineralization observed at Island Copper, Hushamu, Red Dog and Goodspeed areas.

Figure 4 shows the location of current and historical drill holes in Zone 1, including significant intercepts (> 0.1% Cu) of drilling to date as well as the location of two cross-sections detailed in Figure 5 (Section A-A') and Figure 6 (Section B-B').Table 1 details the grades of those intercepts.

Drill hole NW21-03 is of particular interest as it confirms a zone of high-gradegold-copper porphyry mineralization which extends from EC-254 in the west approximately 480 meters horizontally to NW21-03 in the east, and from EC-254 in the north 120 metres horizontally to EC-228 in the south, for an interpreted total extent of at least 500 meters strike length by between at least 240 - 480 metres dip length (Sections A-A' and B-B' in Figure 5 and Figure 6 respectively). Drill holes which intersect this zone have significant mineralized intercepts (>0.1% Cu) ranging from 70 metres to 116 m in length, and an interpreted average true width of 86 metres.

Northisle Copper and Gold Inc. | 1200 - 1166 Alberni St. | Vancouver, BC | V6E 3Z3

www.northisle.ca|[e-mail]

Figure 4: Zone 1 Drill Holes and Significant Intercepts

Figure 4 can be found at full size at the following link: http://www.northisle.ca/wp-content/uploads/2022/01/Figure-4-Zone-1-V5.pdf

It was observed in several historic holes and in NW21-03 assays that a zone with higher molybdenum and rhenium grades occurs above and overlaps with the intercepts noted in Table 1. None of the 2005-2007 holes were analyzed for rhenium. Northisle plans to carry out check re-assays of those holes for Cu, Au, Mo and Re.

Northisle Copper and Gold Inc. | 1200 - 1166 Alberni St. | Vancouver, BC | V6E 3Z3

www.northisle.ca|[e-mail]