NEW BRUNSWICK - Johnson & Johnson announced today that clinical and real-world evidence from its cardiovascular portfolio will be featured at the American College of Cardiology 73rd Annual Scientific Session & Expo (ACC.24) taking place April 6-8, 2024, in Atlanta, Georgia.

Eleven abstracts, including five oral presentations, will showcase data from Company-sponsored studies demonstrating therapeutic benefit of breakthrough medicines, such as XARELTO (rivaroxaban), and interventional technologies, such as those from Abiomed and Biosense Webster, to help treat cardiovascular diseases, including atrial fibrillation (AF) and peripheral artery disease (PAD).

'Cardiovascular disease remains the leading cause of death for adults worldwide and millions more may be at risk of stroke and other life-threatening cardiovascular conditions as the population ages.1 As a global leader in healthcare, we are determined to improve these statistics and empower those living with cardiovascular disease to lead fuller, healthier lives,' said Katie Devine, President, US General Medicines, Canada and Puerto Rico, Johnson & Johnson Innovative Medicine. 'At ACC.24, we look forward to sharing the latest research and innovation from our broad portfolio, including XARELTO, to equip clinicians and researchers with knowledge and insights that can help transform cardiovascular care for all.'

Improving the outlook for people with cardiovascular disease

Johnson & Johnson is committed to elevating the standard of care in cardiovascular diseases and unlocking the potential of medicines and solutions of tomorrow. Several data presentations at ACC.24 demonstrate how the Company is improving outcomes for people living with cardiovascular disease, including older adults and other patient populations often considered hard to treat.

These include: Data from the PIONEER AF-PCI Phase 3 clinical trial evaluating the safety and efficacy of rivaroxaban for reducing the rate of bleeding among elderly and non-elderly patients with nonvalvular AF undergoing percutaneous coronary intervention (Abstract #906-04).

Data from the Real-World Experience of Catheter Ablation for the Treatment of Symptomatic Paroxysmal and Persistent Atrial Fibrillation Using Novel Contact Force Technologies (REAL AF) Registry study evaluating the impact of scar burden on ablation strategy (Abstract #916-10).

Data about Impella heart pumps will be featured in more than 50 presentations, abstracts and posters, including the Danish-German Cardiogenic Shock Trial (DanGer), which is a Late Breaking Clinical Trial (Abstract #406-14).

'Our advancements have changed how cardiovascular diseases are diagnosed and treated and have had a meaningful impact on the lives of millions of patients and families. The data we're presenting at ACC.24 demonstrate how we're continuing to deliver on our commitment,' said Tim Schmid, Executive Vice President and Worldwide Chairman, Johnson & Johnson MedTech. 'We are intent on elevating the standard of care in cardiovascular diseases and, with our partners, are leading research in areas like nonvalvular AF, stroke, and acute coronary syndrome. The real-world and clinical evidence presented at ACC.24 will provide cardiology teams with critical information to help deliver improved care for their patients.'

About Johnson & Johnson

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

Cautions Concerning Forward-Looking Statements

This press release contains 'forward-looking statements' as defined in the Private Securities Litigation Reform Act of 1995 regarding product development and the potential benefits and treatment impact of rivaroxaban. The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of Janssen Research & Development, LLC, Janssen Biotech, Inc., Janssen Pharmaceuticals, Inc. and/or Johnson & Johnson. Risks and uncertainties include, but are not limited to: challenges and uncertainties inherent in product research and development, including the uncertainty of clinical success and of obtaining regulatory approvals; uncertainty of commercial success; manufacturing difficulties and delays; competition, including technological advances, new products and patents attained by competitors; challenges to patents; product efficacy or safety concerns resulting in product recalls or regulatory action; changes in behavior and spending patterns of purchasers of health care products and services; changes to applicable laws and regulations, including global health care reforms and trends toward health care cost containment.

Contact:

Tesia Williams

Email: TWilli65@its.jnj.com

Tel: 202-809-4599

Raychel Kruper

Email: investor.relations@its.jnj.com

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