Jaguar Health, Inc. announced that on March 29, 2018, Dr. Ari Azhir notified the Board of Directors of the company of her intention to resign as a member of the Board, effective upon the close of business on March 29, 2018, including from her role as a member of the Audit Committee and Compensation Committee. Dr. Azhir is resigning to focus on other opportunities and her decision did not involve any disagreement with the company, its management or the Board. Dr. Azhir served as a director of the company since 2016. On March 29, 2018, the Board, by resolution as contemplated in the company's bylaws, appointed Mr. Jonathan B. Siegel, age 44, to fill the vacancy created by Dr. Azhir's resignation and serve as Class I director of the company until the 2019 annual meeting of stockholders or until his successor is elected and qualified. Mr. Siegel is founder of JBS Healthcare Ventures.