Hansa Medical AB announced that enrollment has been finalized in the US investigator-initiated Phase II study with lead candidate IdeS in highly sensitized patients. A total of 17 patients have been enrolled in the study (ClinicalTrials.gov Identifier: NCT02426684) at Cedars-Sinai Medical Center with Professor Stanley Jordan as principal investigator. The study aimed at enrolling 10 to 20 patients. Patients had donor specific antibodies (DSAs) and a positive cross-match test prior to IdeS treatment. IdeS effectively reduced the level of DSAs in all patients and turned the cross-match tests from positive to negative, thereby enabling transplantation for all patients. All patients will be followed for six months with respect to safety, kidney function and DSA levels. Professor Jordan commented on the problem of sensitization and how IdeS has improved transplant rates for these patients.