Elicera Therapeutics AB Submits Clinical Trial Application to Evaluate Its CAR T-Cell Therapy in B-Cell Lymphoma
Elicera's drug candidate, ELC-301, constitutes a fourth generation CAR T-cell therapy that targets the CD20 antigen which, like CD19, is expressed on all B-cell lymphoma cells. ELC-301 is armed with Elicera's iTANK-technology platform to elicit a dual mode-of-action and a broad attack on cancer by also activating the patients' own killer T-cells against the whole set of relevant antigen targets on tumor cells, not only against CD19 or CD20. Development and preparations for the ELC-301 study have been aided over the past year by grants from the European Innovation Council (EIC) Accelerator Programme and Vinnova. In combination with existing cash, the EU-funding was sufficient to fully fund the study and the Vinnova grant will to be used to develop an automated CAR T-cell manufacturing process to be implemented as Good Manufacturing Practice .