Cessatech A/S announced that the pharmacokinetic trial (0206) in children has finalised recruitment of all planned patients. The trial is designed as a non-randomised, open-label study in 25 children aged 1-17 years needing premedication for placement of a peripheral venous catheter for general anaesthesia related to a surgical procedure. The analgesic and sedative properties of the CT001 nasal spray is expected to be beneficial in this setting. The pharmacokinetic data in children are needed for the planned modelling and simulation studies of CT001.

Modelling and simulation studies may under the right circumstances replace traditional trials through extrapolation of e.g. efficacy from adults to children and thus a minimum of clinical trials need to be done in children during drug development. In the 0206 trial, pharmacokinetic data for all relevant age groups will be obtained for use in the planned modelling and extrapolation studies.