Blueprint Medicines Corporation announced leadership transitions for the company's research and development organization. Effective as of January 11, 2021, Becker Hewes, M.D., currently Senior Vice President, Clinical Development, will succeed Andy Boral, M.D., Ph.D., as Chief Medical Officer, and Dr. Boral will transition to a new role as Executive Vice President, Clinical Development. With his promotion, Dr. Hewes will be responsible for clinical development, clinical operations, pharmacovigilance, translational medicine and biostatistics. In his new role, Dr. Boral will advise on clinical development, regulatory and business development strategy across the company's portfolio. Drs. Hewes and Boral will report to Fouad Namouni, M.D., President, Research & Development. In addition, Marion Dorsch, Ph.D., has notified the company of her intention to resign as the company's Chief Scientific Officer to pursue other career opportunities. Her resignation will be effective March 1, 2021, and the company has initiated a search for her replacement. Dr. Hewes brings 20 years of industry and clinical experience in oncology and hematology, including achieving the approval of three tyrosine kinase inhibitors. Previously, he served as Blueprint Medicines' Senior Vice President, Clinical Development from May 2020 to January 2021. Before joining industry, he conducted immuno-oncology research at the Emory Vaccine Center while treating patients as a pediatric oncologist at Children's Healthcare of Atlanta. Dr. Hewes holds an M.D. from the Georgetown University School of Medicine and a B.S. from Vanderbilt University.