Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On January 4, 2022, Joseph Baroldi informed Avidity Biosciences, Inc. (the "Company") of his intention to resign as Chief Operating Officer of the Company to pursue a new opportunity. His last day at the Company will be January 21, 2022. The Company has entered into a post-employment consulting agreement with Mr. Baroldi for a term of six months. Under this agreement, Mr. Baroldi will be compensated at a rate of $350 per hour, and his outstanding equity awards will continue to vest throughout the duration of the term.

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