Item 5.07. Submission of Matters to a Vote of Security Holders.

The Company held its 2021 Annual Meeting on June 15, 2021. In connection with the Annual Meeting, there were 95,457,198 shares outstanding as of the record date, which was April 22, 2021, of which 78,321,287 shares, or approximately 82.05%, were present or represented by proxy. At the Annual Meeting, stockholders voted on the following items:

Proposal 1: Election of Directors



By the vote reflected below, the Company's stockholders elected each of the
following individuals to the Board to hold office until the 2022 Annual Meeting
and until their respective successors are elected and qualified.
Name                                   For            Withheld        Broker Non-Votes
Sol Barer, Ph.D.                    21,612,165       45,018,742              -
Steven Boyd                         26,621,967       40,008,940              -
Suzanne Bruhn, Ph.D.                27,319,716       39,311,191              -
Michael Cola                        24,316,994       42,313,913              -
Phil Gutry                          25,553,121       41,077,786              -
Gilla Kaplan, Ph.D.                 27,350,517       39,280,390
Joseph Miller                       26,432,148       40,198,759              -
Magnus Persson, M.D., Ph.D.         18,860,279       47,770,628              -

The Company understands that the substantial majority of the votes that were withheld for each director nominee were withheld by the Company's largest stockholder, an investment fund directed by one of the members of the Company's board of directors.

Proposal 2: Ratification of Appointment of Independent Registered Public Accounting Firm

The Company's stockholders ratified the appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the year ending December 31, 2021. This proposal was approved by the votes indicated below:


     For            Against        Abstain        Broker Non-Votes
  78,266,029        43,239         12,019                -





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