Certain Ordinary Shares of Ascletis Pharma Inc. are subject to a Lock-Up Agreement Ending on 20-JAN-2019. These Ordinary Shares will be under lockup for 173 days starting from 31-JUL-2018 to 20-JAN-2019. Details: The controlling shareholders have agreed to lock-up restrictions for a period of six months from the listing date which is expected to be August 1, 2018 The shares held by controlling shareholders will be subject to a lock-up of further six months from the expiry of first lock-up period such that on disposal of such shares they cease to be a controlling shareholder of the company. The shareholders, CBC Investment Fifteen Limited, CBC Investment Twelve Limited, Broad Street Investments Holding (Singapore) Pte. Ltd, MBD Bridge Street 2015 Investments (Singapore) Pte. Ltd., Tasly International Capital Limited, Shunda Machinery Co., Limited and Qianhai Ark (Cayman) Investment Co., Limited have agreed to lock-up restrictions for a period of 180 days commencing on the date of this prospectus.