The board of directors of Ascentage Pharma Group International announced that Mr. Zhao Qun has tendered his resignation as a non-executive Director with effect from March 31, 2021 in order to devote more time for his fund investment business and other personal businesses. The Board appointed Dr. David Sidransky as an additional independent non-executive Director with effect from March 31, 2021. As such, pursuant to the articles of association of the Company, Dr. Sidransky shall hold office until the first general meeting of the company after his appointment, being the upcoming annual general meeting of the company (the "AGM"), and be subject to re-election by the Shareholders at the AGM.