Achillion Pharmaceuticals, Inc. announced the appointment of Steven Zelenkofske, D.O. to the position of Executive Vice President and Chief Medical Officer, effective immediately. He will assume responsibility for the clinical development of the company's oral factor D small molecule portfolio of compounds to treat complement-mediated diseases. In addition, the company also announced the expansion of its clinical development group with the recent appointments of Laura Barrow, Pharm.D. to the position of Vice President, Clinical Operations and Head of Project Management, and Marc Uknis, M.D. to the position of Vice President of Clinical Development, Head of Nephrology Therapeutics. Dr. Zelenkofske brings more than 20 years of industry development experience, most recently as Chief Medical Officer of UniQure, a clinical stage gene therapy company, and previously as Chief Medical Officer of Regado Biosciences. He has also held leadership positions at Astra-Zeneca, Sanofi-Aventis, Boston Scientific and Novartis. Dr. Barrow has been in industry over 30 years developing several drugs from the clinic to market. She has the breadth and depth of knowledge and experiences in drug development, clinical operations, project management, and compliance in both large pharma and smaller biotech companies including Roche, Bristol-Myers Squibb, Pfizer and Synergy. Most recently, she worked at Synergy Pharmaceuticals where she progressed a lead program from early phase 2 to a marketed compound.