10x Genomics, Inc. announced the launch of its Xenium Prime 5K Pan-Tissue and Pathways panel. The new assay features an enhanced chemistry to increase plex by an order of magnitude while delivering excellent per-gene sensitivity, improved specificity and spatial fidelity, integrated multimodal cell segmentation. The high-plex Xenium Prime 5K assay enables a new level of exploration for pathways, biomarkers, ligand-receptor pairings and cell-cell interactions.

Key features include: Highest plex Xenium panel for comprehensive profiling of cell types and states and cell signaling pathways across multiple tissue and disease types; Excellent data quality to unlock mechanisms of disease, therapeutics and cell behavior. The Xenium Prime 5K assay is optimized for performance and paired with 10x Genomics' advanced multimodal cell segmentation, enabling high sensitivity, specificity and spatial fidelity; Rapid turnaround time with easy, tissue-agnostic workflows. 10x Genomics' throughput enables researchers to analyze up to 472 mm² of tissue in six days or less; Easily customizable with up to 100 additional genes to capture customers' specific research needs; Rigorously designed and developed using single cell RNA-seq data from dozens of different organs and tissues, gene expression profiles from hundreds of cell types and a screen of more than 750,000 peer-reviewed publications to pinpoint highly cited biomarkers.

The Xenium Prime 5K assay, optimized for human and mouse species, is now available for preorder and is expected to ship next month.