Valuation: Protagonist Therapeutics, Inc.

Market Cap 8.89B 7.98B 7.35B 6.68B 12.63B 834B 12.99B 88.01B 35.07B 447B 33.38B 32.67B 1,412B P/E 2026 *
26.8x
P/E 2027 * 494x
Enterprise Value 8.32B 7.46B 6.87B 6.24B 11.82B 780B 12.15B 82.31B 32.79B 418B 31.21B 30.55B 1,321B EV / Sales 2026 *
14.7x
EV / Sales 2027 * 34.7x
Free-Float
96.86%
Yield 2026 *
-
Yield 2027 * -
1 day+0.26%
1 week-2.84%
Current month-5.93%
1 month-5.20%
3 months-9.16%
6 months+37.14%
Current year+56.01%
1 week 128
Extreme 128
143.3
1 month 126.39
Extreme 126.39
152.18
Current year 77
Extreme 77
160.81
1 year 77
Extreme 77
160.81
3 years 15.05
Extreme 15.05
160.81
5 years 6.91
Extreme 6.91
160.81
10 years 4.47
Extreme 4.47
160.81
Manager TitleAgeSince
Chief Executive Officer 69 30/11/2008
Director of Finance/CFO 52 17/04/2022
Chief Tech/Sci/R&D Officer - 31/03/2026
Director TitleAgeSince
Director/Board Member 69 30/11/2008
Chairman 71 18/03/2014
Director/Board Member 68 30/06/2016
Date Insider Type Main position Quantity % Market Cap. Importance
30/09/26 Exercice

Chief Financial Officer

175,887 0.2718%
10/09/26 Exercice

Chief Executive Officer

21,834 0.0337%
03/09/26 Don

Chief Executive Officer

-510 0.0008%
Change 5-day change 1-year change 3-year change Capi.($)
+0.26%-2.84%+63.72%+779.66% 8.87B
+0.01%+11.10%+60.83%+70.43% 68.22B
+1.22%+9.56%+15.97%+90.23% 59.82B
+0.24%+1.35%+23.78%+97.55% 56.07B
+1.60%+19.44%+28.80%+112.95% 47.67B
-1.32%+4.78%+29.15%+40.40% 45.95B
-3.54%-0.60%+207.76%+879.50% 43.29B
-3.33%+6.90%+22.78%+48.07% 35.66B
-2.19%-3.71%+90.94%+66.33% 34.73B
+2.92%+14.41%-37.74%+403.12% 25.47B
Average -0.41%+4.63%+50.60%+258.82% 43B
Weighted average by Cap. -0.40%+5.33%+51.01%+193.04%

Financials

2026 *2027 *
Net sales 567M 509M 469M 426M 806M 53.18B 828M 5.61B 2.24B 28.49B 2.13B 2.08B 90.07B 240M 215M 199M 180M 341M 22.53B 351M 2.38B 947M 12.07B 902M 883M 38.15B
Net income 354M 317M 292M 265M 502M 33.15B 516M 3.5B 1.39B 17.76B 1.33B 1.3B 56.14B 42.68M 38.28M 35.28M 32.04M 60.63M 4B 62.33M 422M 168M 2.14B 160M 157M 6.78B
Net Debt -576M -517M -476M -433M -819M -54.03B -841M -5.7B -2.27B -28.95B -2.16B -2.12B -91.51B -567M -509M -469M -426M -806M -53.18B -828M -5.61B -2.24B -28.49B -2.13B -2.08B -90.06B
Projected Income Statement - Annual - Protagonist Therapeutics, Inc.
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
149
Date Price Change Volume
10/11/26 US$136.26 +0.26% 528,488
09/11/26 US$135.90 +2.92% 607,111
06/11/26 US$132.04 -2.38% 972,945
05/11/26 US$135.26 -5.66% 584,678
04/11/26 US$143.37 +2.23% 777,232
Trader
Investor
Global
Quality
ESG MSCI
BB
MarketScreener Ratings - Protagonist Therapeutics, Inc.
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
14
Last Close Price
136.26USD
Average target price
182.36USD
Spread / Average Target
+33.83%
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