Item 4.01 Change in Registrant's Certifying Accountant.

(b) Appointment of New Auditor

On December 19, 2022, Scientific Industries, Inc (the "Company") engaged Macias Gini & O'Connell LLP ("MGO") as its new independent registered public accounting firm beginning with the fiscal period commencing on July 1, 2022 and ending December 31, 2022. The change in the Company's independent registered public accounting firm was approved by the Company's Audit Committee and Board of Directors.

During the fiscal years ended June 30, 2022 and 2021 and the subsequent interim periods through the date of this Current Report, neither the Company nor anyone on its behalf consulted with MGO regarding any of the following:





    (i)  The application of accounting principles to a specific transaction,
         either completed or proposed;
    (ii) The type of audit opinion that might be rendered on the Registrant's
         financial statements, and none of the following was provided to the
         Registrant:


       (a) a written report; or
       (b) oral advice that MGO concluded was an important factor considered by
           the Company in reaching a decision as to an accounting, auditing or
           financial reporting issue; or


          Any matter that was subject of a disagreement as that term is defined in
    (iii) Item 304(a)(1)(iv) of Regulation S-K, or a reportable event, as
          described in Item 304(a)(1)(v) of Regulation S-K

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