Rhythm Pharmaceuticals, Inc. announced that Keith Gottesdiener, M.D., intends to step down as Chief Executive Officer, President and a member of the Board of Directors. The Board has formed a search committee and retained an executive search firm to assist in identifying Dr. Gottesdiener's successor. Dr. Gottesdiener plans to serve in his current role until the completion of the Company's submission of its New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA).