On February 6, 2019, in connection with Charles R. Eyler’s upcoming retirement on February 15, 2019 from Puma Biotechnology, Inc. as Senior Vice President of Finance and Administrator and Treasurer, the Compensation Committee of the Board of Directors of the Company approved entering into a Transition and General Release Agreement with Mr. Eyler whereby he will receive a cash payment of $425,189 in connection with his retirement.