On February 16, 2023, Mr. Robert Besthof, NRx Pharmaceuticals, Inc.'s Head of Operations and Chief Commercial Officer, notified the Company of his resignation. Mr. Besthof will continue to work at the company in order to effect an orderly transition of his responsibilities. Mr. Besthof's last day with the company has yet to be agreed.

The company is currently in discussions with Mr. Besthof regarding a continuing role as a part-time advisor to the company.