Item 5.07 Submission of Matters to a Vote of Security Holders

On June 8, 2022, MarketAxess Holdings Inc. (the "Company") held its 2022 Annual Meeting of Stockholders (the "2022 Annual Meeting"). A total of 34,088,100 shares of common stock were present or represented by proxy at the 2022 Annual Meeting, representing 91.01% of the issued and outstanding shares entitled to vote at the meeting. The proposals voted upon and the final results of the vote were as follows:

Proposal 1 - Election of Directors. The results were as follows:



                                                               Broker
Director                      For        Against    Abstain   Non-Votes
Richard M. McVey           30,838,802   1,653,676   227,054   1,368,568
Nancy Altobello            32,457,206    255,930     6,396    1,368,568
Steven L. Begleiter        32,482,144    230,935     6,453    1,368,568
Stephen P. Casper          29,062,869   3,650,243    6,420    1,368,568
Jane Chwick                32,262,487    450,648     6,397    1,368,568
Christopher R. Concannon   32,255,077    458,062     6,393    1,368,568
William F. Cruger          31,362,294   1,341,922   15,316    1,368,568
Kourtney Gibson            32,523,385    189,740     6,407    1,368,568
Justin G. Gmelich          32,477,275    230,668    11,589    1,368,568
Richard G. Ketchum         32,476,314    236,804     6,414    1,368,568
Xiaojia Charles Li         31,997,618    710,747    11,167    1,368,568
Emily H. Portney           32,581,457    131,680     6,395    1,368,568
Richard L. Prager          30,621,717   2,091,416    6,399    1,368,568

Proposal 2 - Ratification of the selection of PricewaterhouseCoopers LLP as the Company's independent registered public accounting firm for the year ending December 31, 2022. The results were as follows:



   For        Against    Abstain
32,333,669   1,667,506   86,925

Proposal 3 - Advisory vote on the compensation of the Company's named executive officers as disclosed in the proxy statement pursuant to the SEC's compensation disclosure rules (referred to as the "say-on-pay" proposal). The results were as follows:



   For        Against    Abstain   Broker Non-Votes
31,400,988   1,156,413   162,131      1,368,568

Proposal 4 - Approval of the Company's 2022 Employee Stock Purchase Plan. The results were as follows:



   For       Against   Abstain   Broker Non-Votes
32,509,854   205,665    4,013       1,368,568

For more information on the 2022 Annual Meeting and the foregoing proposals, see the Company's 2022 Proxy Statement.

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