Lipum (publ) has entered a collaboration with researchers at the Karolinska Institute (KI), Division of Rheumatology at the Department of Medicine in Sweden. Lipum's drug candidate SOL-116 has been developed for treatment of chronic inflammatory diseases and a clinical phase 1 safety study is currently ongoing. In parallel, preclinical studies on the target molecule bile salt-stimulated lipase (BSSL) and SOL-116 are also prioritised.

The intention of the research collaboration between Lipum and KI is to thoroughly explore the role of BSSL in the immune system in general and in rheumatoid arthritis in particular and to further elucidate the mode of action of the anti-BSSL antibody and drug candidate SOL-116. The Division of Rheumatology at KI conduct research on the etiology, molecular mechanisms, treatments, and outcome of many of the most severe chronic rheumatic inflammatory diseases. The research is translational spanning from molecular biology to clinical research.