On May 1, 2015, Acucela Inc. approved a shareholder proposal to remove the following directors from the company's board of directors: Peter A. Kresel, Glen Y. Sato, Michael T. Schutzler and Brian T. O'Callaghan. Additionally, on May 3, 2015, Brian O'Callaghan resigned his position as President and Chief Executive Officer of the company, effective immediately.