On January 5, 2021, Mark Stenhouse departed from his position as the Exact Sciences Corporation’s General Manager, Screening. Pat Setji, the Company’s Vice President, Business Operations, will succeed Mr. Stenhouse until a permanent replacement is named. Ms. Setji has served in multiple sales and marketing leadership roles at Pfizer, Eli Lilly and the Company during the last 20 years. In connection with his departure, Mr. Stenhouse will assist with the transition as an advisor and remain a non-executive employee of the Company through March 31, 2021.