Item 7.01 Regulation FD Disclosure.

On January 5, 2022, Day One Biopharmaceuticals, Inc. (the "Company") updated its corporate presentation.

Additionally, on January 5, 2022, the Company issued a press release announcing that it will present at the 40th Annual J.P. Morgan Healthcare Conference ("J.P. Morgan Conference") held virtually on January 11, 2022 at 10:30 a.m. Eastern Time. Dr. Jeremy Bender chief executive officer will present virtually.

A copy of the press release and the updated corporate presentation are attached as Exhibits 99.1 and 99.2, respectively, to this Current Report on Form 8-K. The corporate presentation will also be available on the Company's website in the Events & Presentations section at www.dayonebio.com.

The information in Item 7.01 of this report, including Exhibit 99.1 and Exhibit 99.2, shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended ("Exchange Act"), or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act, nor shall it be deemed incorporated by reference into any other filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

Item 8.01 Other Events.

On January 5, 2022 the Company disclosed that based on its current operating plan, the Company's management believes that the Company has sufficient capital resources to fund anticipated operations into 2024.

Forward Looking Statements

This Current Report on Form 8-K contains "forward-looking" statements within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. Forward-looking statements can be identified by words such as: "anticipate," "intend," "plan," "goal," "seek," "believe," "project," "estimate," "expect," "strategy," "future," "likely," "may," "should," "will" and similar references to future periods. These statements are subject to numerous risks and uncertainties that could cause actual results to differ materially from what we expect. Examples of forward-looking statements include the Company's management's beliefs regarding the sufficiency of the Company's capital resources. Further information on potential risk factors that could affect our business and its financial results are detailed in our most recent Quarterly Report on Form 10-Q for the quarter ended September 30, 2021 filed with the Securities and Exchange Commission (SEC), and other reports as filed with the SEC. We undertake no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.

Item 9.01 Financial Statements and Exhibits.



(d)     Exhibits

 Exhibit                                     Description
 Number

99.1           Press Release

99.2           Corporate Presentation

104          Cover Page Interactive Data File (embedded within the Inline XBRL document).

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